A Study of Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)



Status:Completed
Conditions:Neurology, Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 64
Updated:11/17/2018
Start Date:April 2009
End Date:June 2012

Use our guide to learn which trials are right for you!

Multiple Subcutaneous Doses of LY2127399, an Anti-BAFF Human Antibody, in Subjects With Relapsing-Remitting Multiple Sclerosis

To look at the ability of LY2127399 to reduce magnetic resonance imaging (MRI) lesions at 12,
16, 20, and 24 weeks compared to placebo.


Inclusion Criteria:

- 18 through 64 years of age diagnosed with RRMS, who can walk without aid or rest for
at least 200 meters (approximately 1/10 of a mile).

- Women who can become pregnant must use birth control.

Exclusion Criteria:

- Have had a live vaccination within 12 weeks before randomization, or intend to have a
live vaccination during the course of the study.

- Have had had recent surgery or are scheduled to have surgery during the study.

- Are immunocompromised or have evidence of active infection [such as hepatitis,
tuberculosis or, human immunodeficiency virus (HIV)].

- Have been on certain drugs that are being studied for RRMS or have recently received
prescription drugs to treat RRMS.

- Have had a recent serious infection.

- Have serious or uncontrolled illnesses other than RRMS.

- Have clinically significant blood test values.

- Have multiple or severe drug allergies.

- Have contraindications for MRI "scanning" or claustrophobia (fear of an enclosed
space) that cannot be managed.
We found this trial at
28
sites
?
mi
from
Newport News, VA
Click here to add this to my saved trials
?
mi
from
Akron, OH
Click here to add this to my saved trials
?
mi
from
Biddeford, ME
Click here to add this to my saved trials
Charlotte, North Carolina 28207
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
?
mi
from
Denver, CO
Click here to add this to my saved trials
Farmington Hills, Michigan 48334
?
mi
from
Farmington Hills, MI
Click here to add this to my saved trials
?
mi
from
Franklin, TN
Click here to add this to my saved trials
?
mi
from
Fullerton, CA
Click here to add this to my saved trials
?
mi
from
Green, OH
Click here to add this to my saved trials
?
mi
from
Greensburg, PA
Click here to add this to my saved trials
Greenville, South Carolina 29605
?
mi
from
Greenville, SC
Click here to add this to my saved trials
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
?
mi
from
Lexington, KY
Click here to add this to my saved trials
?
mi
from
Lubbock, TX
Click here to add this to my saved trials
?
mi
from
Memphis, TN
Click here to add this to my saved trials
?
mi
from
Naples, FL
Click here to add this to my saved trials
?
mi
from
Northbrook, IL
Click here to add this to my saved trials
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
?
mi
from
Plantation, FL
Click here to add this to my saved trials
?
mi
from
Raleigh, NC
Click here to add this to my saved trials
?
mi
from
Roanoke, VA
Click here to add this to my saved trials
?
mi
from
Round Rock, TX
Click here to add this to my saved trials
?
mi
from
Sarasota, FL
Click here to add this to my saved trials
?
mi
from
Schenectady, NY
Click here to add this to my saved trials
?
mi
from
Sofia,
Click here to add this to my saved trials
?
mi
from
Toms River, NJ
Click here to add this to my saved trials
?
mi
from
Tucson, AZ
Click here to add this to my saved trials