Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

A global, multi-center, open-label, observational registry to capture safety and
effectiveness data related to ExAblate Neuro, an MRI guided focused ultrasound device
designed to lesion tissue deep within the brain using sound waves without the need for
craniotomy. This registry includes certain regional and country specific approved thalamotomy
and pallidotomy procedures using ExAblate Neuro for the treatment of various neurologic
disorders such as essential tremor, Parkinson's movement disorders, and neuropathic pain.
Treatment targets/indications are country/region dependent based on approved labeling within
that region.

Inclusion Criteria:

- Meets labeling indication for use per information for prescribers

- Target is accessible by Focused Ultrasound per treatment planning parameters

Exclusion Criteria:

- Do not agree to participate or who are unlikely to participate over an extended period
of time