Evaluating Raised Intracranial Pressure Using MR Elastography

The goal of this study is to evaluate the brain elasticity in patients with idiopathic
intracranial hypertension (IIH) and other forms of raised intracranial pressure, such as
obstructive hydrocephalus. Investigators will evaluate for a correlation between brain
stiffness and opening pressure on lumbar puncture. Investigators will also evaluate for
changes in brain stiffness after interventions that are aimed at lowering intracranial
pressure, including lumbar punctures, medications, and surgical interventions, such as
ventriculoperitoneal shunts. Lastly, investigators will compare MR elastography measurements
to other forms of noninvasive methods of detecting raised intracranial pressure, including
optical coherence tomography (OCT) measurements of the retinal nerve fiber layer (RNFL) and
indirect signs of raised intracranial pressure on MRI.

All subjects will have the following inclusion criteria:

- Group 1: Papilledema from idiopathic intracranial hypertension and other forms of
elevated intracranial pressure, including obstructive hydrocephalus

- Group 2: Patients without raised intracranial pressure.

All subjects will have the following exclusion criteria:

- Age <18

- Pregnancy (self-reported)

- Individuals for whom MR is contraindicated