The Effect of Microneedle Pretreatment on Topical Anesthesia
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - 60 |
| Updated: | 11/29/2018 |
| Start Date: | January 2014 |
| End Date: | June 2015 |
This study evaluates the role of microneedle pretreatment in the speed at which anesthesia
develops after application of topical 4% lidocaine.
develops after application of topical 4% lidocaine.
This study evaluates whether the time to anesthesia with topical 4% lidocaine can be
accelerated with the use of microneedle pretreatment. The study will evaluate the anesthesia
as a randomized split-body study where each subject serves as their own control. The study
will be performed on the volar forearm. Prior to application of the topical 4% lidocaine, one
arm will be exposed to a microneedle pretreatment on a microneedle roller and the other arm
will be exposed to sham microneedle treatment that will consist of a flat roller with no
microneedles. Then pain will be assessed with the use of a spring loaded needle lancet that
will be applied at 2 min, 5 min, 10 min, and 30 minutes after treatment.
accelerated with the use of microneedle pretreatment. The study will evaluate the anesthesia
as a randomized split-body study where each subject serves as their own control. The study
will be performed on the volar forearm. Prior to application of the topical 4% lidocaine, one
arm will be exposed to a microneedle pretreatment on a microneedle roller and the other arm
will be exposed to sham microneedle treatment that will consist of a flat roller with no
microneedles. Then pain will be assessed with the use of a spring loaded needle lancet that
will be applied at 2 min, 5 min, 10 min, and 30 minutes after treatment.
Inclusion Criteria:
- Healthy volunteers
Exclusion Criteria:
- Allergy to lidocaine
- Smokers
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