Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

Veterans with PTSD are a highly vulnerable population with tremendous disability and unmet
needs. Few VA patients with PTSD now actually receive evidence-based psychotherapy because
current exposure-based treatments have low uptake. The project goal is to expand the range of
PTSD psychotherapy treatments available at Veterans Administration Medical Centers. This
pilot trauma recovery proposal takes the next step in translating a brief efficacious
psychotherapy developed and tested for panic disorder, Panic Focused Psychodynamic
Psychotherapy (PFPP) for Veterans with PTSD at the VA New York Harbor Healthcare System (VA
NYHHCS). PFPP was developed, manualized, and studied in RCTs over the past two decades. We
hope that Trauma-Focused Psychodynamic Psychotherapy (TFPP), an adaptation of PFPP, with its
high response rates in panic disorder with/without agoraphobia, and non-exposure protocol,
will fill crucial gaps in Veteran care. A major challenge facing psychotherapy research is
translating and implementing efficacious therapies to the community. No psychodynamic
psychotherapy for anxiety or PTSD has achieved this in the US. This pilot RCT represents a
paradigm shift in its approach to trauma. TFPP will be the only PTSD treatment for Veterans
to incorporate Veterans' input into refinement of the treatment as this project progresses.
TFPP targets aspects of traumatic experience and approaches Veterans' lives more broadly than
the symptom-focused treatments the VA currently offers our traumatized Veterans.

Inclusion Criteria:

- Reporting moderate PTSD, as defined by a CAPS score of >40

- Have at least one of the following history with CPT and/or PE:

- offered and declined

- dropped out of treatment

- been determined unsuitable by their treatment team

- received treatment but continue to experience symptoms meeting entrance criteria.

- Require stabilization on psychiatric medication for 2 month period prior to entry into
study to avoid confounding treatments

Exclusion Criteria:

- Presence of SCID-5 assessed psychotic disorder, bipolar disorder, or substance use
that would interfere with trial demands

- Severe suicidality that would require immediate crisis management

- Organic mental syndromes based on diagnosis or Montreal Cognitive Assessment
(MoCA)<22, delirium, or unstable medical conditions that would interfere with trial
demands

- Inability to meet trial demands.