Celebrex Total Knee Arthroplasty Study



Status:Terminated
Conditions:Arthritis, Chronic Pain, Osteoarthritis (OA)
Therapuetic Areas:Musculoskeletal, Rheumatology
Healthy:No
Age Range:18 - 80
Updated:12/6/2018
Start Date:November 2006
End Date:July 2007

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Multicenter, Double Blind, Randomized, Placebo Controlled Trial Of The Efficacy And Safety Of Usual Care Plus Celecoxib Compared To Placebo For Peri-Operative And Rehabilitation Pain Control And Return To Function In Osteoarthritis Patients Undergoing Total Knee Arthroplasty

This study will investigate the benefits of administering celecoxib (Celebrex), a selective
cyclooxygenase -2 (COX-2) inhibitor, in treating osteoarthritis (OA) subjects undergoing
elective unilateral primary total knee arthroplasty (TKA) from the pre-operative phase to the
management of post total knee replacement pain, and through the 6 weeks of physical therapy
and rehabilitation.


Inclusion Criteria:

- The subject is a male or female 18 years or older with osteoarthritis of the knee
scheduled to undergo elective unilateral primary total knee arthroplasty because of
OA, performed under a standardized regimen of anesthesia and procedure.

Exclusion Criteria:

- Subject has a history of inflammatory arthritis (e.g. rheumatoid arthritis, ankylosing
spondylitis) other than osteoarthritis.
We found this trial at
6
sites
Chicago, Illinois 60611
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Chicago, IL
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Aurora, Colorado 80045
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Aurora, CO
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Bellaire, Texas 77401
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Bellaire, TX
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Englewood, Colorado 80110
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Englewood, CO
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Houston, Texas 77030
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Houston, TX
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Philadelphia, Pennsylvania 19134
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Philadelphia, PA
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