Oral Factor XIa Inhibitor for the Prevention of New Ischemic Stroke in Patients Receiving Aspirin and Clopidogrel Following Acute Ischemic Stroke or Transient Ischemic Attack (TIA)
| Status: | Recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease, Neurology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Neurology |
| Healthy: | No |
| Age Range: | 40 - Any |
| Updated: | 4/5/2019 |
| Start Date: | November 30, 2018 |
| End Date: | August 31, 2021 |
| Contact: | Recruiting sites have contact information. Please contact the sites directly. If there is no contact information |
| Email: | Clinical.Trials@bms.com |
| Phone: | please email |
A Global, Phase 2, Randomized, Double-Blind, Placebo-Controlled, Response-Adaptive Dose-Ranging Study of BMS-986177, an Oral Factor XIa Inhibitor, for the Prevention of New Ischemic Stroke or New Covert Brain Infarction in Patients Receiving Aspirin and Clopidogrel Following Acute Ischemic Stroke or Transient Ischemic Attack (TIA)
The purpose of this clinical study is to determine whether the addition of an oral Factor XIa
Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary
stroke prevention. The safety of this treatment will also be studied.
Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary
stroke prevention. The safety of this treatment will also be studied.
For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com
Inclusion Criteria:
- Male and Female ≥40 years of age
- Acute Ischemic Stroke or Transient Ischemic Attack
- Intracranial or Extracranial Atherosclerotic Plaque proximal to the affected brain
area
Exclusion Criteria:
- Predicted inability to swallow study medication
- Any condition that, in the opinion of the Investigator, contraindicates anticoagulant
therapy or would have an unacceptable risk of bleeding
- Use of thrombolytic therapy or mechanical thrombectomy for treatment of acute ischemic
stroke event
Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
34
sites
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3400 Spruce St
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
(215) 662-4000
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
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Greensboro, North Carolina 27401
Phone: 336-516-9104
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Temple University Hospital On January 18, 1892 a three-story house at 3403 North Broad Street...
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