Histologic Comparison of Healing After Tooth Extraction With Ridge Preservation Using Two Different Xenografts
| Status: | Not yet recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 100 |
| Updated: | 12/9/2018 |
| Start Date: | January 2019 |
| End Date: | January 2020 |
| Contact: | Kerri Font, DDS, MS |
| Email: | kerri.font@ucdenver.edu |
| Phone: | 303-724-0695 |
The purpose of this study is to compare the speed of bone healing of the two most commonly
used xenografts on the market, Bio-Oss® and Salvin-Oss® using a tooth extraction ridge
preservation model in participants scheduled for tooth extraction and subsequent receipt of a
dental implant. Researchers hypothesize that there will be additional vital bone at 16-20
weeks with Salvin-Oss®.
used xenografts on the market, Bio-Oss® and Salvin-Oss® using a tooth extraction ridge
preservation model in participants scheduled for tooth extraction and subsequent receipt of a
dental implant. Researchers hypothesize that there will be additional vital bone at 16-20
weeks with Salvin-Oss®.
This study focuses on xenografts to preserve alveolar bone after tooth extraction prior to
placement of a dental implant. Extraction sites that are not grafted for ridge preservation
may lose up to 50 percent of their ridge width the first year after extraction. Xenografts
are one of several products on the market used to maintain ridge width after tooth
extraction. This study aims to compare the two most commonly used, FDA-approved xenografts on
the market, Bio-Oss® and Salvin-Oss, in the preservation of alveolar bone after extraction of
non-molar teeth.
The primary objective of this study is to histologically evaluate and compare the percentage
of new bone formation in healing extraction sockets of non-molar teeth grafted with Bio-Oss®
versus Salvin-Oss®. The secondary aim is to observe clinical changes in ridge height and
ridge width after grafting with these two materials.
placement of a dental implant. Extraction sites that are not grafted for ridge preservation
may lose up to 50 percent of their ridge width the first year after extraction. Xenografts
are one of several products on the market used to maintain ridge width after tooth
extraction. This study aims to compare the two most commonly used, FDA-approved xenografts on
the market, Bio-Oss® and Salvin-Oss, in the preservation of alveolar bone after extraction of
non-molar teeth.
The primary objective of this study is to histologically evaluate and compare the percentage
of new bone formation in healing extraction sockets of non-molar teeth grafted with Bio-Oss®
versus Salvin-Oss®. The secondary aim is to observe clinical changes in ridge height and
ridge width after grafting with these two materials.
Inclusion Criteria:
- At least 18 years of age.
- Consent to be in the study.
- Planned for non-emergent dental treatment.
- American Society of Anesthesiologist Class I or II.
- Require extraction of a single-rooted non-molar tooth.
- Committed to have the dental implant placed at the site of extraction 16-20 weeks
after extraction and ridge preservation.
- Adequate restorative space for implant-retained restoration.
- > 10mm alveolar bone height without impingement on the maxillary sinus or inferior
alveolar canal.
- Root location and angulation that would be consistent with the subsequent implant
placement.
- Roots with minimum of 10mm of radiographic bone support.
- Root angulation similar to the angulation of the implant to be placed at the site.
Exclusion Criteria:
- < 18 years old.
- Currently pregnant.
- Require antibiotic prophylaxis prior to dental procedures as outlined by the 2017
American Heart Association guidelines.
- Decisionally challenged individuals.
- Current smokers.
- American Society of Anesthesiologist Class III or IV.
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