Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer

PRIMARY OBJECTIVES:

I. Assess the feasibility and acceptability of the CFS intervention in patients with advanced
lung and gynecologic (GYN) cancer (stages III or IV) who have clinically significant levels
of fear of cancer progression (FOP) or cancer-related distress.

SECONDARY OBJECTIVES:

I. Assess preliminary effects of the intervention on FOP, cancer-specific distress, anxiety,
depression, overall symptom distress, metacognitions, and mindfulness.

OUTLINE:

Patients attend CFS psychosocial intervention consisting of 7 nurse-led sessions (session 1
in-person and sessions 2-7 via video conferencing) over 45 minutes each for 8 weeks. Patients
also complete home practice assignments comprising attention training technique and
mindfulness practice sessions after each session.

After completion of study intervention, patients are followed up at week 12.

Inclusion Criteria:

- Patients with gynecologic (GYN) and lung cancer will be recruited

- Stage III or IV disease

- At least 3 months from initial diagnosis

- Receiving disease-focused treatment or active surveillance mode

- A score of ≥ 34 on the Fear of Progression Questionnaire-Short Form (SF) or ≥ 24 on
the Impact of Event Scale-Revised

- All subjects must have the ability to understand and the willingness to sign a written
informed consent

Exclusion Criteria:

- Current severe depression or psychosis; significant cognitive impairment

- Patients enrolled in hospice care or who opt to receive no further disease-focused
treatment

- Patients who are currently receiving ongoing psychiatric treatment

- Non-English speaking