Influence of Exercise Type, Pain Mechanisms, and Biopsychosocial Contributions to Pain Relief in Those With Fibromyalgia
| Status: | Recruiting |
|---|---|
| Conditions: | Fibromyalgia, Pain |
| Therapuetic Areas: | Musculoskeletal, Rheumatology |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 12/20/2018 |
| Start Date: | February 3, 2017 |
| End Date: | January 2022 |
| Contact: | Marie K Hoeger Bement, PT, PhD |
| Email: | mariehoeger.bement@marquette.edu |
| Phone: | 414-288-6738 |
Exercise Specificity and Endogenous Pain Modulation
The purpose of this study is to investigate the influence different types of exercise, pain
mechanisms, and biopsychosocial contributions on how people with and without fibromyalgia
report pain. Exercise will be performed with the arm at a submaximal intensity. Participants
will undergo a variety of pain assessments, including clinical questionnaires and pain
perception. This study will improve our understanding of how people with and without
fibromyalgia respond to different resistance exercise types and whether physical activity and
body composition has an influence on the response.
mechanisms, and biopsychosocial contributions on how people with and without fibromyalgia
report pain. Exercise will be performed with the arm at a submaximal intensity. Participants
will undergo a variety of pain assessments, including clinical questionnaires and pain
perception. This study will improve our understanding of how people with and without
fibromyalgia respond to different resistance exercise types and whether physical activity and
body composition has an influence on the response.
Fibromyalgia is a chronic widespread pain condition that is mostly prevalent in middle-aged
women. Exercise is one of the few therapies that can alleviate fibromyalgia symptoms. Despite
exercise being a major component of rehabilitation, exercise guidelines are unclear, often
leading to symptom exacerbation and low compliance. Previous research has demonstrated that
women with fibromyalgia may have different post-exercise pain responses when undergoing an
exercise task. Factors critical to optimal exercise prescription are not known, including the
most effective type of exercise, mechanisms responsible for pain relief, and biopsychosocial
influences. This study investigates the use of exercise as a nonpharmacological pain
management tool for people with fibromyalgia.
The purpose of this study is to investigate the acute exercise-induced pain response after
isometric and dynamic muscle contractions in people with and without fibromyalgia. All
participants will attend up to three sessions with approximately one week between sessions at
a metropolitan university laboratory setting. Participants will perform different types of
submaximal exercise for a maximum of ten minutes and complete pain assessments each session.
Pain and psychosocial influences are measured with multiple established clinical
questionnaires. Pressure pain sensitivity is tested by application of a mechanical stimulus
to the arms and legs. To investigate a participant's innate ability to inhibit pain, the
mechanical stimulus will be assessed with and without limb submersion in a cold-water bath.
Physical activity is measured via questionnaire and use of activity monitors, while body
composition is measured with a dual energy x-ray absorptiometry scan.
women. Exercise is one of the few therapies that can alleviate fibromyalgia symptoms. Despite
exercise being a major component of rehabilitation, exercise guidelines are unclear, often
leading to symptom exacerbation and low compliance. Previous research has demonstrated that
women with fibromyalgia may have different post-exercise pain responses when undergoing an
exercise task. Factors critical to optimal exercise prescription are not known, including the
most effective type of exercise, mechanisms responsible for pain relief, and biopsychosocial
influences. This study investigates the use of exercise as a nonpharmacological pain
management tool for people with fibromyalgia.
The purpose of this study is to investigate the acute exercise-induced pain response after
isometric and dynamic muscle contractions in people with and without fibromyalgia. All
participants will attend up to three sessions with approximately one week between sessions at
a metropolitan university laboratory setting. Participants will perform different types of
submaximal exercise for a maximum of ten minutes and complete pain assessments each session.
Pain and psychosocial influences are measured with multiple established clinical
questionnaires. Pressure pain sensitivity is tested by application of a mechanical stimulus
to the arms and legs. To investigate a participant's innate ability to inhibit pain, the
mechanical stimulus will be assessed with and without limb submersion in a cold-water bath.
Physical activity is measured via questionnaire and use of activity monitors, while body
composition is measured with a dual energy x-ray absorptiometry scan.
Inclusion Criteria:
- Fibromyalgia
- Healthy Controls without fibromyalgia
- Stable medical management plan for four weeks prior to participation in the study.
- Physical Activity Readiness Questionnaire (PAR-Q)
- English proficiency
Exclusion Criteria:
- Elbow arthritis
- Carpal tunnel syndrome
- Cervical surgery
- Cerebrovascular accident / stroke
- Multiple sclerosis
- Parkinson's disease
- Any central neurodegenerative disease
- Traumatic brain injury
- Peripheral neuropathy of the upper extremity
- Myocardial infarction
- Chronic obstructive pulmonary disease
- Any unstable medical or psychiatric condition
- Diabetes mellitus
- Active cancer
- Lymphedema of the upper extremity
- Claustrophobia
- Raynaud's phenomenon
- Osteoporosis
- Major depressive disorder
- Bipolar disorder
- Rheumatoid arthritis
- Lupus
- Polymyalgia rheumatica
- Pregnancy
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