Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome
Status: | Recruiting |
---|---|
Conditions: | Other Indications, Ocular |
Therapuetic Areas: | Ophthalmology, Other |
Healthy: | No |
Age Range: | Any - 18 |
Updated: | 12/20/2018 |
Start Date: | May 30, 2018 |
End Date: | June 2020 |
Contact: | Niklaus H Mueller |
Email: | niklaus.mueller@ucdenver.edu |
Phone: | 3037249995 |
This study involves the collection ocular lens tissue from individuals with Down syndrome and
age-matched controls at the time of cataract surgery.
age-matched controls at the time of cataract surgery.
Individuals with Down syndrome have an increased rate of cataract. The reason for this
increase is unclear. Normally, once cataracts become a significant impairment, an
ophthalmologist will determine when cataract surgery should be performed. When this surgery
is performed, cataractous tissues are cut out and discarded with medical waste. In this
study, these tissue will be collected and protein analysis performed to determine what
changes in different proteins are found in Down syndrome lenses as compared to normal
cataractous lenses.
increase is unclear. Normally, once cataracts become a significant impairment, an
ophthalmologist will determine when cataract surgery should be performed. When this surgery
is performed, cataractous tissues are cut out and discarded with medical waste. In this
study, these tissue will be collected and protein analysis performed to determine what
changes in different proteins are found in Down syndrome lenses as compared to normal
cataractous lenses.
Inclusion Criteria:
- Undergoing cataract surgery for lens extraction.
Exclusion Criteria:
- Known genetic cause other than Down syndrome causing cataract.
We found this trial at
1
site
13123 E 16th Ave
Aurora, Colorado 80045
Aurora, Colorado 80045
(720) 777-1234
Phone: 303-724-9995
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