Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails
| Status: | Completed |
|---|---|
| Conditions: | Dermatology |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | November 2005 |
| End Date: | May 2008 |
| Contact: | David G Armstrong, DPM, PhD |
| Email: | david.armstrong@rosalindfranklin.edu |
| Phone: | 847-578-8440 |
Topical Collagen-Silver Versus Standard Care Following Phenol Ablation of Ingrown Nails: A Randomized Controlled Trial
This study's purpose is to prospectively determine whether topical therapy with an oxidized
regenerated cellulose collagen-silver compound is more effective than the current standard
of topical antibiotic therapy for care following the removal of an ingrown toenail. Eighty
adult patients with ingrown toenails will be recruited. Each patient will randomly be
assigned to apply either topical silver sulfadiazine cream (standard antibiotic) or the
novel collagen-silver compound to their nail bed daily, following removal of the ingrown
portion of nail. Patients will return for follow up visits weekly, until healing has
occurred or twelve weeks have passed. Healing will be defined as resolution of drainage and
inflammatory changes surrounding the nail border.
regenerated cellulose collagen-silver compound is more effective than the current standard
of topical antibiotic therapy for care following the removal of an ingrown toenail. Eighty
adult patients with ingrown toenails will be recruited. Each patient will randomly be
assigned to apply either topical silver sulfadiazine cream (standard antibiotic) or the
novel collagen-silver compound to their nail bed daily, following removal of the ingrown
portion of nail. Patients will return for follow up visits weekly, until healing has
occurred or twelve weeks have passed. Healing will be defined as resolution of drainage and
inflammatory changes surrounding the nail border.
Inclusion Criteria:
- Ingrown toenails will be defined as any incurvated nail border that digs into the
skin of the nail fold and causes pain and discomfort
Exclusion Criteria:
- Patients with immunocompromised states
- chronic steroid use
- diabetes mellitus
- collagen vascular disease
- HIV infection
- Cellulitis proximal to the hallux interphalangeal joint or peripheral vascular
disease will be excluded
- We will define peripheral vascular disease as the absence of one or more pedal pulses
or the presence of dystrophic changes to the integument
We found this trial at
2
sites
Click here to add this to my saved trials
Click here to add this to my saved trials