Measuring Single-Serving Grain Intake

The aim of this study is to identify compounds that are found in blood and urine and are
derived from a single meal of whole grain oat or whole grain wheat intake so that
epidemiological studies can be conducted to provide more accurate associations between whole
grain intake and health.

Inclusion Criteria:

- 21 to 75 years of age

- Voluntarily agree to participate and sign an informed consent form

Exclusion Criteria:

- Body weight less than 110 lbs.

- Have a body mass index below 19 or above 38 kg/m2

- Known (self-reported) allergy or adverse reaction to study foods

- Women who have given birth during the previous 12 months or who are pregnant/lactating
or who plan to become pregnant during the study

- History of bariatric surgery or nutrient malabsorption disease (such as celiac
disease), Crohn's disease, diabetes, or metabolic disorders that may interfere with
the study

- History of certain cancer diagnosis or treatment in the last 3 years

- Smoking or use of tobacco products in the past 6 months

- Suspected or known strictures, fistulas or physiological/mechanical GI obstruction

- Use of certain medications or supplements (prescription or over-the-counter) that may
interfere with the study objectives, including blood thinning medications

- Unable or unwilling to give informed consent or communicate with study staff

- Self-report of alcohol or substance abuse within the past 12 months and/or current
treatment for these problems (long-term participation in Alcoholics Anonymous is not
an exclusion)

- Other medical, psychiatric, or behavioral factors that in the judgment of the
Principal Investigator may interfere with study participation or the ability to follow
the intervention protocol