Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer

OBJECTIVES:

Primary

- Determine the prevalence, severity, and interference due to physical and psychological
symptoms experienced (over a 4 to 5 week period) by patients with invasive primary
breast, lung, prostate, or colorectal cancer who are being followed on an outpatient
basis at ECOG institutions.

Secondary

- Determine if the number of symptom-related interventions are related to the providers'
perception of symptom severity.

- Determine whether physical symptoms are more commonly prioritized and treated compared
to psychological symptoms.

- Determine the percentage of patients who experience a significant reduction in
moderate-to-severe symptoms and characterize the determinants of symptom relief.

- Determine the focus and scope of interventions chosen by oncologists to improve the
symptom control of patients seen in outpatient clinics.

OUTLINE: This is an open-label, multicenter study. Patients are stratified according to
disease type, prevalence according to gender, race/ethnicity, age, and type of treatment.

Patients complete the M.D. Anderson Symptom Assessment Inventory and other questionnaires,
rating the symptoms most frequently found in this patient group and how much these symptoms
interfere with mood and activity-related domains, on day 1 and again between days 28-35.

At the same time points, a healthcare provider (treating physician, nurse, or physician
assistant) completes the Revised Edmonton Staging System for Cancer Pain questionnaire,
assessing the patient's cancer pain on the basis of mechanism of pain, incidental pain,
psychological distress and addictive behavior, and cognitive function, for clinical prognosis
on pain control.

PROJECTED ACCRUAL: A total of 2,310 patients and their physicians will be accrued for this
study.

DISEASE CHARACTERISTICS:

- Being seen in an outpatient setting at an ECOG-affiliated academic institution, a CGOP
site, or a CCOP site

- In pretreatment, active treatment, or follow-up for their cancer

- Clinically diagnosed invasive cancer involving at least 1 of the following primary
sites:

- Breast

- Lung

- Prostate

- Colorectal

- Hormone receptor status not specified

PATIENT CHARACTERISTICS:

- Male or female

- Menopausal status not specified

- Willing to complete a written survey between day 28 and day 35 after completion of the
baseline assessment

- Able to read, write, and understand English

- No significantly impaired cognitive status which, in the opinion of the investigator,
would hinder ability to provide responses

PRIOR CONCURRENT THERAPY:

- Not specified