Comparing Acute Aerobic and Resistance Exercise

Young and middle-aged to older adults who are physically active or not physically active will
participate in two moderate to vigorous intensity exercise bouts: aerobic exercise and
resistance training exercise. Blood will be collected to assess immune function and
metabolism.

Inclusion Criteria:

- "Young" Adults: ages 18-30

- "Older" Adults: ages 55-75 and if a female postmenopausal

- Participants classified as "trained" must participate in at least 30 minutes of
moderate to vigorous intensity cardiovascular activity at least 3 days per week and
engage in resistance training for all of the major muscle groups approximately 2 days
/ week. They must have upheld this activity for the past 3 months

- Participants classified as "untrained" must be participating in less than 30 minutes
of moderate to vigorous intensity cardiovascular activity and less than 2 days of
resistance training per week for at least the last 3 months.

Exclusion Criteria:

- Have any contraindications to moderate to vigorous exercise

- Range of motion restrictions that would prevent them from participating in aerobic or
resistance training with proper form (they must be ambulatory)

- aking medications (prescription or over the counter) known to influence immune
function, including daily NSAID's, beta blockers, statins, bisphosphonates, or
steroids.

- Have known cardiovascular, respiratory, metabolic, or renal disease, with the
exception of controlled hypertension (as defined by resting BP below 140/90) and/or
controlled asthma (self-reported).

- Be pregnant

- Be unable to complete all visits (i.e. must not be planning to leave the Houston area
long-term before concluding their participation in the study which will span several
weeks)

- Fall outside of a BMI range of (18.5 - 30)

- Consume alcohol or recreational drugs for 24h prior to visits

- Older women cannot be pre-menopausal (must have not had a menses for at least 12
months)

- Unable to speak or read English

- Participants must not have scheduling conflicts that would prevent them from reporting
to the laboratory of integrated physiology 4 times over the course of the study