Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease
| Status: | Recruiting |
|---|---|
| Conditions: | Chronic Pain, Chronic Pain, Irritable Bowel Syndrome (IBS), Gastrointestinal |
| Therapuetic Areas: | Gastroenterology, Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/8/2019 |
| Start Date: | February 26, 2019 |
| End Date: | July 2019 |
| Contact: | Carrie :L Falling, BPhty(Hons) |
| Email: | carrie.falling@postgrad.otago.ac.nz |
| Phone: | +6421558513 |
This study evaluates nervous system hypersensitivity in individuals with inflammatory bowel
disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain. Previous results and
current literature suggest that MSK pain in IBD may be influenced by hypersensitivity of the
central nervous system, termed central sensitization. However, specific mechanisms
contributing to pain experiences are unknown. Therefore, primary aims are to explore aspects
of central sensitization through sensory testing in this population, and to investigate
association of psychological and IBD features to sensory profiles. This study hypothesizes
that IBD patients with MSK pain will demonstrate altered sensory function, and
IBD/psychosocial features will be associated with altered sensory functioning and worse pain
experiences.
disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain. Previous results and
current literature suggest that MSK pain in IBD may be influenced by hypersensitivity of the
central nervous system, termed central sensitization. However, specific mechanisms
contributing to pain experiences are unknown. Therefore, primary aims are to explore aspects
of central sensitization through sensory testing in this population, and to investigate
association of psychological and IBD features to sensory profiles. This study hypothesizes
that IBD patients with MSK pain will demonstrate altered sensory function, and
IBD/psychosocial features will be associated with altered sensory functioning and worse pain
experiences.
Inclusion Criteria:
- Adults (18 years of age or older)
- Clinical diagnosis of IBD or healthy control
Exclusion Criteria: Participants with IBD (with and without MSK pain) will be excluded if
they report any of the following:
- pregnancy
- current history of drug or alcohol abuse
- any condition resulting in altered sensation such as: nerve injuries, neurological
conditions (e.g. stroke, multiple sclerosis, and Parkinson's disease)
- surgery within the last 3 months
We found this trial at
1
site
1 Medical Center Dr
Lebanon, New Hampshire 03756
Lebanon, New Hampshire 03756
(603) 650-5000
Phone: 642-155-8513
Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
Click here to add this to my saved trials
