Below Knee DVT Study
| Status: | Terminated |
|---|---|
| Conditions: | Cardiology, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/15/2019 |
| Start Date: | September 2014 |
| End Date: | July 2015 |
Is Therapeutic Anticoagulation Necessary for the Treatment of Distal Deep Venous Thrombosis of the Lower Extremity? A Randomized, Controlled Trial
Hospitalized patients are at risk of developing blood clots in the legs (Deep Vein Thrombosis
or DVT), which can lead to death if those clots break off and migrate to the lungs. We know
that if there is a blood clot in the large leg veins near the hips and in the thighs,
treating these patients with high-doses of blood thinners reduces the risk of these deaths.
It is unclear if treating blood clots in the calf with high doses of blood thinners is better
than using low doses. In this study, after being diagnosed with a blood clot in the calf,
patients will be treated with either low dose or high dose enoxaparin (Lovenox), a blood
thinner. We will then see if low dose blood thinner has similar results as high dose blood
thinner.
or DVT), which can lead to death if those clots break off and migrate to the lungs. We know
that if there is a blood clot in the large leg veins near the hips and in the thighs,
treating these patients with high-doses of blood thinners reduces the risk of these deaths.
It is unclear if treating blood clots in the calf with high doses of blood thinners is better
than using low doses. In this study, after being diagnosed with a blood clot in the calf,
patients will be treated with either low dose or high dose enoxaparin (Lovenox), a blood
thinner. We will then see if low dose blood thinner has similar results as high dose blood
thinner.
Inclusion Criteria:
- Patients over the age of 18 admitted to a trauma or general surgery service will be
eligible
- Patients diagnosed with an isolated distal DVT
- Able to obtain informed consent
Exclusion Criteria:
- Patients with a previous diagnosis of hypercoagulability
- Patients on chronic anticoagulation
- Patients with a history of heparin induced thrombocytopenia
- Patients have preexisting contraindications to anticoagulation
- Patients in renal failure requiring adjusted enoxaparin dosing
- Pregnant patients
We found this trial at
1
site
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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