Obesity and Endogenous Oxalate Synthesis
| Status: | Recruiting |
|---|---|
| Conditions: | Obesity Weight Loss, Nephrology, Nephrology |
| Therapuetic Areas: | Endocrinology, Nephrology / Urology |
| Healthy: | No |
| Age Range: | 19 - 65 |
| Updated: | 1/19/2019 |
| Start Date: | January 1, 2013 |
| End Date: | December 31, 2022 |
| Contact: | Billy Tingle, RN |
| Email: | billy@uab.edu |
| Phone: | 205-934-3671 |
The goal of this proposal is to determine the contribution and significance of obesity to
urinary oxalate excretion and thus calcium oxalate kidney stone disease. Successful
completion of the study will provide insight into the link between obesity and kidney stone
disease and should identify future strategies to treat this disease.
urinary oxalate excretion and thus calcium oxalate kidney stone disease. Successful
completion of the study will provide insight into the link between obesity and kidney stone
disease and should identify future strategies to treat this disease.
Inclusion Criteria:
- Body Mass Index (BMI) < 30
- Calcium oxalate stone formers with passage or removal of a kidney stone containing >
50% calcium oxalate
- Type 2 Diabetics with fasting glucose > 126 mg/dL or hemoglobin A1c greater than or
equal to 6.5%
Exclusion Criteria:
- Any disease that will affect the urinary excretion of oxalate, calcium or another ion
that will compromise the interpretation of results.
- Abnormal urine chemistries or blood metabolic profiles
- A glomerular filtration rate (GFR) or estimated GFR < 60 mls/min
- Pregnancy
- Body Mass Index (BMI) > 32
We found this trial at
1
site
1720 2nd Ave S
Birmingham, Alabama 35233
Birmingham, Alabama 35233
(205) 934-4011
Principal Investigator: Kyle D Wood, MD
Phone: 205-934-3671
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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