The Use of Fractionated Exhaled Nitric Oxide in the Diagnosis and Assessment of Disease Activity of Eosinophilic Esophagitis



Status:Recruiting
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:5 - 18
Updated:3/10/2019
Start Date:January 31, 2019
End Date:July 28, 2019
Contact:Cristoniel Abrenica, MD
Email:noeoehouston@gmail.com
Phone:(713) 500-5663

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria
The purpose of the study is to evaluate of the relationships between fractionated exhaled
nitric oxide, disease activity, and symptom severity in patients with eosinophilic
esophagitis compared to those without eosinophilic esophagitis.


Inclusion Criteria:

- Pediatric patient who will undergo esophagogastroduodenoscopy with biopsies at
Children's Memorial Hermann Hospital, as part of the standard of care in the
evaluation of EoE

- Able to perform the single-breath exhalation for the hand-held analyzer, "NIOX VERO®"
(Aerocrine, Sweden)

- Signed informed consent by a parent or legal guardian

- Signed assent form by the child/adolescent subjects 7-18 years of age

Exclusion Criteria:

- Past medical history of asthma, allergic rhinitis, IBD, parasitic infection, hay fever
and any exposure to smoking (including secondhand smoke) because these disorders are
known to affect the FeNO levels

- Active respiratory tract infections at the time of FeNO evaluation because this can
affect the result of the FeNO as well

- Asthma questionnaire and/or Spirometry test consistent with asthma
We found this trial at
1
site
University of Texas Health Science Center at Houston
7000 Fannin St
Houston, Texas 77030
(713) 500-4472
University of Texas Health Science Center at Houston The University of Texas Health Science Center...
?
mi
from
Houston, TX
Click here to add this to my saved trials