Hepatic Vein Flow During Orthotopic Liver Transplantation as Predictive Factor for Postoperative Graft Function



Status:Recruiting
Healthy:No
Age Range:Any
Updated:1/25/2019
Start Date:February 20, 2018
End Date:June 30, 2019
Contact:Yoshihisa Morita, MD
Email:ymorita1@hfhs.org
Phone:313-970-1282

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Trial Summary
Trial Overview
Inclusion Criteria

Hepatic Vein Flow Assessment With Transesophageal Echocardiography for Postoperative Graft Function Prediction in Orthotopic Liver Transplantation

Hepatic vein flow (HVF) assessment using transesophageal echocardiography (TEE) has a
potential to predict postoperative graft function in orthotopic liver transplant (OLT).
Investigators will measure HVF using TEE and assess the correlation with postoperative graft
function indices such as prolonged total bilirubin level.

During OLT, intraoperative TEE assessment of HVF (systolic and diastolic), and indices of
postoperative graft function including time to normalization of INR, platelet, and total
bilirubin. HVF was calculated with hepatic vein area (cm2) x hepatic vein velocity (ml/s) in
systole and diastole during the neohepatic phase. Investigators defined HVF index (HVFi) as:
HVF/donor liver size (kg). Investigators did ROC analysis to assess the predictive power for
prolonged INR, platelet, and total bilirubin.

Inclusion Criteria:

Orthotopic liver transplants which uses TEE intraoperatively Must be Piggy back technique -

Exclusion Criteria:

TEE absolute contraindication patient refusal
We found this trial at
1
site
HFHS
Detroit, Michigan 48202
Phone: 313-874-4420
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Detroit, MI
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