E-cigarettes, Nicotine Inhaler, and Blood Vessel Function



Status:Recruiting
Conditions:Smoking Cessation, Tobacco Consumers
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:21 - 45
Updated:1/26/2019
Start Date:January 11, 2017
End Date:December 2021

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Trial Summary
Trial Overview
Inclusion Criteria

The Effects of Electronic Cigarettes on Endothelial Function and Oxidative Stress

Randomized controlled trial of electronic cigarettes with nicotine, without nicotine,
nicotine inhaler, and sham-control on endothelial function, oxidative stress and sympathetic
nerve activity

Participants will have an acute exposure on 4 occasions1) e-cigarette with nicotine, 2)
e-cigarette without nicotine, 3) nicotine inhaler, 4) sham control and undergo ECG recording
for heart rate variability, endothelial function measurement using ultrasound ("FMD") and
blood tests for oxidative stress markers.

Inclusion Criteria:

- Healthy

Exclusion Criteria:

- Cardiac disease

- Respiratory disease

- Diabetes mellitus
We found this trial at
1
site
UCaliforniaLA
Los Angeles, California 90095
Phone: 310-206-6672
?
mi
from
Los Angeles, CA
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