Tai Chi and eCB in Women
| Status: | Not yet recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 40 - 70 |
| Updated: | 2/23/2019 |
| Start Date: | April 1, 2019 |
| End Date: | December 31, 2020 |
| Contact: | Chwan-Li Shen, PhD |
| Email: | leslie.shen@ttuhsc.edu |
| Phone: | 8067432815 |
Tai Chi and eCB in Postmenopausal Women
The endocannabinoid system (ECS) is widely found in central and peripheral systems, and the
immune system. Moderate-intensity aerobic exercise has shown to increase circulatory
endocannabinoids. In this study, we will study Tai Chi, a mind-body moderate-intensity
exercise, intervention for its effects on ECS in women. A pre-post design trial will be
conducted on 18 qualified subjects. We will measure plasma eCB levels at baseline, before and
after 4th session of Tai Chi. All data will be analyzed statistically at p<0.05.
immune system. Moderate-intensity aerobic exercise has shown to increase circulatory
endocannabinoids. In this study, we will study Tai Chi, a mind-body moderate-intensity
exercise, intervention for its effects on ECS in women. A pre-post design trial will be
conducted on 18 qualified subjects. We will measure plasma eCB levels at baseline, before and
after 4th session of Tai Chi. All data will be analyzed statistically at p<0.05.
The endocannabinoid system (ECS) is widely found in central and peripheral systems, and the
immune system. Emerging studies have shown endocannabinoid plays a role in appetite, pain
sensation, control of chronic pain, macronutrient metabolism, mood/mood disorder, and
regulation of immune cell functions. Moderate-intensity aerobic exercise has shown to
increase circulatory endocannabinoids. Moderate-intensity exercise improves cognition,
memory, and wellbeing in adults. Exercisers experience decreased tension, depression, and
anger. Therefore, these findings in humans suggest a likely relationship for exercise
effecting well-being via ECS. In this study, we will study Tai Chi, a mind-body
moderate-intensity exercise, intervention for its effects on ECS in women. A pre-post design
trial will be conducted on 15 qualified subjects. All subjects will be assigned to Tai Chi
group for one week including 3 sessions, 60 minutes per session, on 3 non-consecutive days.
We will measure plasma eCB levels at baseline, before and after 4th session of Tai Chi. All
data will be analyzed statistically at p<0.05.
immune system. Emerging studies have shown endocannabinoid plays a role in appetite, pain
sensation, control of chronic pain, macronutrient metabolism, mood/mood disorder, and
regulation of immune cell functions. Moderate-intensity aerobic exercise has shown to
increase circulatory endocannabinoids. Moderate-intensity exercise improves cognition,
memory, and wellbeing in adults. Exercisers experience decreased tension, depression, and
anger. Therefore, these findings in humans suggest a likely relationship for exercise
effecting well-being via ECS. In this study, we will study Tai Chi, a mind-body
moderate-intensity exercise, intervention for its effects on ECS in women. A pre-post design
trial will be conducted on 15 qualified subjects. All subjects will be assigned to Tai Chi
group for one week including 3 sessions, 60 minutes per session, on 3 non-consecutive days.
We will measure plasma eCB levels at baseline, before and after 4th session of Tai Chi. All
data will be analyzed statistically at p<0.05.
Inclusion Criteria:
1. Postmenopausal women (menopause is defined as the absence of menstrual period for 12
months, not related to pregnancy/lactation, hormonal contraception). Age 40-70 years
old with BMI between 25-35 kg/m2.
2. English literacy.
Exclusion Criteria:
1. prior experience with mind-body practice (e.g., TC, Qi Gong, yoga, meditation).
2. Severe medical limitations (i.e., dementia, symptomatic heart or vascular disease, or
recent stroke) precluding full participation.
3. Medical/neurologic or other systemic diseases affecting the musculoskeletal systems
(i.e. polio/Parkinson's/ multiple sclerosis, etc. in addition to cerebral vascular
accident or stroke) and diabetes with peripheral neuropathy affecting their
sensory/balance.
4. taking pain/anti-inflammatory and sleep medications within the 3 months before study
starts.
5. taking hormone-replacement therapy within the 3 months before study starts.
We found this trial at
1
site
Click here to add this to my saved trials
