A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)



Status:Recruiting
Conditions:Blood Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - 80
Updated:3/20/2019
Start Date:April 1, 2019
End Date:January 2022

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Trial Summary
Trial Overview
Inclusion Criteria
The purpose of this study is to evaluate the feasibility and outcomes of a research pre- and
peri-transplant optimization program (R-PPOP) to improve multiple domains of health including
physical function, cognitive function, mental health, and diet and nutrition for patients
planning to undergo or undergoing hematopoietic stem cell transplantation (HCT).


Patient Inclusion Criteria:

- Plan to undergo an allogeneic hematopoietic stem cell transplant for any cancer or
non-cancer illness within the next 6 months

- Age 18-80 years

Patient Exclusion Criteria:

- Both patient and caregiver are unable to read and follow directions in English (ok if
only patient cannot read and follow directions in English as caregiver will be able to
help).

- Any absolute contraindications to exercise:

- recent (< 6 months) acute cardiac event;

- unstable angina;

- uncontrolled dysrhythmias causing symptoms or hemodynamic compromise;

- symptomatic aortic stenosis;

- uncontrolled symptomatic heart failure;

- acute pulmonary embolus;

- acute myocarditis or pericarditis;

- suspected or known dissecting aneurism; or

- coronary artery disease.

- Functional impairment resulting in inability to exercise

Caregiver inclusion criteria

- Identified by patient as their primary caregiver

- Age 18-80 years

Caregiver exclusion criteria
We found this trial at
1
site
Duke University Adult Bone Marrow Transplant Clinic
Durham, North Carolina 27705
Principal Investigator: Anthony Sung, MD
Phone: 919-684-7115
?
mi
from
Durham, NC
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