Cognitive Rehab for Parkinson's



Status:Not yet recruiting
Conditions:Cognitive Studies, Cognitive Studies, Parkinsons Disease
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:50 - Any
Updated:2/13/2019
Start Date:September 16, 2019
End Date:August 8, 2022
Contact:Sandra L Kletzel, PhD BA
Email:Sandra.Kletzel@va.gov
Phone:(708) 202-5735

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Cognitive Rehabilitation for Veterans With Parkinson's Disease

This study will examine the feasibility of an at-home cognitive training program that
incorporates both memory training and online computerized cognitive training (CCT) software.
Data will also be collected to determine if this program improves thinking and memory as well
as everyday function. The hypothesis is that memory and cognitive training combined ,
compared to memory training alone or will lead to greater improvements in cognitive
performance and daily function.

The objective of this study is to examine feasibility of an at-home cognitive rehabilitation
program that incorporates both prospective implementation intentions strategies (PRIIS) and
an existing web-based executive function (EF) computerized cognitive training (CCT) software
for Veterans with Parkinson's disease (PD) and to collect pilot data to determine the impact
of this program on cognition and everyday function. The central hypothesis is that CCT+PRIIS,
compared to CCT alone and an active control group, will lead to greater improvements in
cognitive performance and daily function. This innovative study uses a set of on-line
training games that target aspects of EF susceptible in PD and trains the transfer of
cognitive benefits to everyday function, using PRIIS, for Veterans with PD and mild cognitive
impairment in executive function. Additionally, training is conducted at home allowing for
convenience and flexibility for participants.

Inclusion Criteria:

- Veterans who seek services at Hines VA Hospital

- Diagnosis of PD as determined by the UK Parkinson's Disease Society Brain Bank
Diagnostic Criteria

- Meet criteria for having mild cognitive impairment

- Receiving stable (i.e., no changes in medication and medication dose) medication and
who are expected to remain on stable medication for the duration of the RCT

- Speak and read English

Exclusion Criteria:

- Dementia

- Failure to demonstrate decision making capacity

- Cholinesterase inhibitor medication

- History of deep brain stimulation surgery

- Severe depression

- Severe anxiety

- Severe apathy
We found this trial at
1
site
Hines, Illinois 60141
Principal Investigator: Sandra L. Kletzel, PhD BA
Phone: 708-202-8387
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from
Hines, IL
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