MBSR in a Hispanic Immigrant Population in St. Louis



Status:Not yet recruiting
Healthy:No
Age Range:18 - Any
Updated:2/17/2019
Start Date:December 1, 2019
End Date:January 1, 2024

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Adaptation and Implementation of a Mindfulness Intervention Among a Hispanic Immigrant Population in St. Louis

Hispanics are the largest ethnic group in the US as well as the fastest growing. Yet, despite
being such a large population group, Hispanics are under-studied and under-represented in
most studies of health, psychological well-being, and mind-body interventions. For many
Hispanic immigrants, life in the U.S. carries multiple socio-economic stressors, which places
them at higher risk for depression and other poor health-related quality of life outcomes.
Mindfulness-based stress reduction (MBSR) is a group-based training shown to reduce stress
and improve overall well-being. There is a quality gap about adaptation and implementation of
MBSR programs in community settings and among Hispanic immigrants. This K23 seeks to adapt
and test the implementation of an MBSR intervention among under-resourced Hispanic immigrants
in St. Louis guided by methods and frameworks from the field of dissemination and
implementation (D&I) science as applied to community settings. Implementation research of
mindfulness-based interventions among Hispanic immigrant populations is justifiable under
several conditions, including ineffective clinical engagement with this population, risk or
resilience factors that are unique to the Hispanic community, and lack of cultural relevance
of many evidence-based MBIs.

This career development award will establish Dr. Parra as a clinical translational
investigator focused on mind-body interventions for Hispanic immigrant populations. This K23
award will provide her the support needed to develop expertise in 3 areas: (1) Training to
conduct well designed randomized clinical trials; (2) Dissemination and Implementation (D&I)
science; and (3) Mindfulness research. To achieve these goals, Dr. Parra has assembled an
expert multidisciplinary team in clinical research, D&I, and mindfulness. Her primary mentor,
Dr. Eric Lenze, has extensive experience in conducting randomized clinical trials and
mentoring junior faculty to become independent investigators. Her secondary mentor, Dr. Ross
Brownson, is an internationally recognized and leading expert in D&I science. Her scientific
collaborators and advisors include Dr. Douglas Ziedonis, a leading expert in mindfulness
clinical research and Dr. Tod Braver, a mindfulness research expert. Dr. Parra will also
benefit from the expertise of two renowned researchers in D&I science in the areas of
intervention adaptation (Dr. Ana Baumann) and measuring implementation and feasibility
outcomes (Dr. Rachel Tabak), as well as the experience from a senior MBSR expert (Dr. Jeannie
Kloeckner), and an expert on mental health interventions for Hispanic populations (Dr.
Patricia Cavazos-Rehg). Hispanics are the largest and fastest-growing ethnic group in the US,
currently representing 14 percent of the population. Despite this, Hispanics are seldom
represented in research studies and health promoting programs, in part due to a lack of
cultural appropriateness by researchers and low levels of trust of the research community by
many Hispanics. Using D&I frameworks and methods, Dr. Parra will adapt a Mindfulness Based
Stress Reduction intervention (MBSR-A) among under-resourced Hispanic immigrants in St. Louis
(Aim 1). Dr. Parra will also conduct a pilot feasibility RCT trial among 60 Hispanic
immigrants (Aim 2) to test and measure implementation outcomes including acceptability,
appropriateness and feasibility. This research plan leverages existing institutional
resources at Washington University in St. Louis (WU), including the Healthy Mind Lab from Dr.
Lenze, Dr. Brownson's D&I center, as well as Dr. Lenze's and Dr. Braver's NIH-funded
mindfulness research groups. Finally, this training and research will form the basis for an
R01 application to further study the adoption, implementation and effectiveness of a
Mindfulness intervention in under-resourced Hispanic immigrant populations.

Inclusion Criteria:

- Non-institutionalized adult Hispanic men and women attending community centers in St.
Louis that serve the immigrant population, under resourced (those earning less than
twice the federal poverty line)42, less than five years of having immigrated to the
United States, low to normal English literacy, and no history of cognitive or physical
disability that would prevent participation. Participants must not be currently
involved in any other type of mind-body intervention.

Exclusion Criteria:

- participants with a history of cognitive or physical disability that would prevent
participation.

- participants currently involved in any other type of mind-body intervention.
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Saint Louis, Missouri 63110
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