Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes

A total of 170 participants were initially enrolled in the comprehensive behavioral weight
loss intervention.In this study, investigators will conduct a follow-up visit 3 years after
the completion of the intervention. Only participants who completed the behavioral weight
loss intervention will be enrolled in this study. Participants will undergo testing of body
weight, body composition, physical activity patterns, energy intake patterns, sleep patterns,
resting metabolic rate, and total daily energy expenditure.

Inclusion Criteria:

- Previous enrollment in standard behavioral weight loss intervention (NCT01985568)

- Age 20-60 (This age range has been selected based upon the participants enrolled in
the Parent Trial)

- Capable and willing to give informed consent

- Possess a smartphone to install and utilize the meal timing application

- Capable and willing to wear the Actigraph, ActivPAL and Actiwatch-2 for 24 hours/day
for 28 consecutive days

- Willing to complete the Total Daily Energy Expenditure (TDEE) assessment which
includes multiple urine collections and drinking stable water isotopes

Exclusion Criteria:

- Being considered unsafe to participate as determined by the study physician (Dr.
Catennaci)

- New diagnosis of a medical condition (not observed in the Parent Trial) which may
affect weight or energy metabolism (e.g. depression, CVD, diabetes, uncontrolled
hypertension, untreated thyroid, renal, hepatic diseases)

- Women who became pregnant after completing the Parent Trial

- Current use or use within the last 6 months of prescription or over-the-counter
medications known to affect appetite, weight, and sleep