End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients
| Status: | Completed |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 2/20/2019 |
| Start Date: | October 15, 2017 |
| End Date: | December 30, 2017 |
End-tidal Oxygen Can Reliably Predict the Arterial Partial Pressure of Oxygen Among Emergency Department Patients Undergoing Rapid Sequence Intubation
Recent studies have shown that end tidal oxygen (ETO2) monitoring can be useful to determine
the adequacy of preoxygenation. No study has assessed the correlation between ETO2 values
obtained during preoxygenation to predict the PaO2 in patients undergoing RSI in the ED. Our
objective was to determine whether a novel equation using the ETO2 at the end of
preoxygenation could reliably estimate the partial pressure of arterial oxygen (PaO2) in
critically-ill ED patients undergoing RSI.
the adequacy of preoxygenation. No study has assessed the correlation between ETO2 values
obtained during preoxygenation to predict the PaO2 in patients undergoing RSI in the ED. Our
objective was to determine whether a novel equation using the ETO2 at the end of
preoxygenation could reliably estimate the partial pressure of arterial oxygen (PaO2) in
critically-ill ED patients undergoing RSI.
Rapid Sequence Intubation (RSI) is the preferred and most commonly-used method of definitive
airway management among critically ill emergency department (ED) patients requiring
intubation. Adequate preoxygenation is intended to prolong the safe apnoeic period. Optimal
preoxygenation for ED patient undergoing RSI is best described as a two-part process of
denitrogenation of the functional residual capacity (FRC) and the formation of an oxygen
reservoir within the alveoli. End-tidal O2 (EtO2) has been shown to be a reliable surrogate
marker for denitrogenation. Most of the literature supporting EtO2 as an adequate maker of
adequate preoxygenation has been conducted in the operating room setting. This population
varies significantly from the population requiring endotracheal intubation in the ED. Our
study aim was to show that the use of a gas analyzer measuring the fraction of inspired
oxygen (FiO2) and EtO2 during the preoxygenation phase of ED RSI can reliably predict the
minimal PaO2 at the end of the ED preoxygenation period.
airway management among critically ill emergency department (ED) patients requiring
intubation. Adequate preoxygenation is intended to prolong the safe apnoeic period. Optimal
preoxygenation for ED patient undergoing RSI is best described as a two-part process of
denitrogenation of the functional residual capacity (FRC) and the formation of an oxygen
reservoir within the alveoli. End-tidal O2 (EtO2) has been shown to be a reliable surrogate
marker for denitrogenation. Most of the literature supporting EtO2 as an adequate maker of
adequate preoxygenation has been conducted in the operating room setting. This population
varies significantly from the population requiring endotracheal intubation in the ED. Our
study aim was to show that the use of a gas analyzer measuring the fraction of inspired
oxygen (FiO2) and EtO2 during the preoxygenation phase of ED RSI can reliably predict the
minimal PaO2 at the end of the ED preoxygenation period.
Inclusion Criteria:
- All patients undergoing rapid sequence intubation.
Exclusion Criteria:
- Patients presenting to the emergency department in cardiac or traumatic arrest
- Patients who received bi-level positive airway pressure (BiPAP) as the primary
delivery of preoxygenation.
We found this trial at
1
site
