Human Repeated Insult Patch Test

Inclusion Criteria:

- Adults;

- Subjects must understand and execute an Informed Consent Form that includes a HIPAA
statement;

- Subjects must be considered dependable and able to follow directions

Exclusion Criteria:

- Subjects who are in ill health;

- Subjects who are taking medications other than birth control;

- Female subjects who are pregnant (return positive urine pregnancy test), planning to
become pregnant or lactating during the course of the trial;

- Subjects who have a history of adverse reactions to personal care products, or known
sensitivity to the test materials or their constituents including patch materials;

- Subjects with any active skin disease;

- Subjects who have heavy alcohol consumption;

- Subjects with current use or history of repeated use of street drugs;

- Subjects with a significant past medical history to potentially effect results of
study;

- Subjects with immunization less than 10 days prior to the test patch application;