Treadmill Exercise in Metabolic Syndrome



Status:Recruiting
Conditions:Endocrine
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 65
Updated:2/28/2019
Start Date:January 9, 2019
End Date:July 2019
Contact:Gloria Yeh, MD, MPH
Email:gyeh@bidmc.harvard.edu
Phone:617-754-1419

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The main purpose of this study is to better understand the effects of two types of treadmill
exercise programs that include education and/or techniques that may be helpful for exercise
among individuals with, or at risk for, metabolic syndrome.


Inclusion Criteria:

1. Referred by healthcare provider and given medical clearance for moderate-intensity
exercise

2. At risk for metabolic syndrome, defined as meeting two or more of the following
criteria:

- Obesity or overweight defined as BMI > 25

- Impaired glycemia (fasting blood sugar of ≥ 100 [5.6 mmol/L] or glycated
hemoglobin [A1C] of ≥ 5.7)

- Increased blood pressure (130/85 mmHg or higher) or if you take medicine for high
blood pressure

- Increased fasting levels of triglycerides (≥ 150 or 1.7 mmol/L) or decreased
fasting high-density lipoprotein (HDL) cholesterol (less than 40 mg/dL or 1
mmol/L for men or 50 mg/dL or 1.3 mmol/L for women) or if you take any medicines
for dyslipidemia

3. Between the ages of 18-65

4. No regular physical activity (≥ 3 or more days per week) for the past 3 months

Exclusion Criteria:

1. Contraindications for treadmill exercise determined by their physician (e.g.,
cardiopulmonary limitations or diagnoses) or other inability to do treadmill exercise
(e.g., musculoskeletal restrictions or severe balance impairment)

2. Confirmed diagnosis of coronary artery disease

3. Confirmed diagnosis of diabetes

4. Currently taking a beta blocker or calcium channel blocker medication

5. Uncontrolled and untreated hypertension, defined as a resting blood pressure of 150/90

6. Confirmed diagnosis of chronic obstructive pulmonary disease or other severe lung
dysfunction that may interfere with exercise (e.g., severe asthma)

7. Self-reported psychotic disorder

8. Current practice of mindfulness mediation or mindful movement (e.g., yoga or tai chi),
defined as regular daily practice or >2 classes or self-guided sessions per week in
the past three months.

9. Non-English speaking
We found this trial at
1
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Boston, Massachusetts 02215
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Boston, MA
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