Influence of Yogic Breathwork on CSF Circulation



Status:Not yet recruiting
Healthy:No
Age Range:18 - 65
Updated:3/2/2019
Start Date:June 1, 2019
End Date:February 1, 2021
Contact:Yildiz
Email:yildiz@ohsu.edu
Phone:5034947219

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Quantifying the Influence of Yogic Breathwork on Cerebrospinal Fluid Circulation

The purpose of this research study is to determine the influence of a regular yogic
breathwork intervention on cerebrospinal fluid (CSF) circulation, and to find out primarily
if a regular practice of 8-week yogic breathing would enhance CSF circulation as well as if
the intervention would improve participant's quality of life, quality of sleep, and reduce
existing stress. Half of the participants will receive a set of breathing practices, while
the other half will undergo slow breathing using a delivered and monitored by a breathing
device (Food and Drug Administration approved RESPeRATE).

The purpose of this research protocol is to determine the influence of an 8-week yogic
breathwork intervention on cerebrospinal fluid (CSF) circulation among healthy participants
using a non-invasive real-time phase-contrast magnetic imaging (RT-PCMRI) technique. This aim
will be examined by studying the changes in each participant's pre- and post-intervention CSF
flow dynamics using the non-invasive RT-PCMRI technique during two MRI scans (one before and
one after the 8-week intervention).

The study protocol consists of 20 healthy participants undergoing an 8-week intervention (10
subjects in the breathwork arm and 10 subjects in the slow breathing arm), and pre-and
post-intervention outcome measures.

The two 8-week interventions will be guided by two separate certified experienced yoga
teachers. Both interventions will consist of 60-minute weekly group on-site sessions
(1day/week) with a 20-minute daily home sessions (in between on-site sessions; 6 days/week)
using home-aid practice materials. A benchmark of at least 8 on-site sessions and 15-min
daily home practice (4 days/week) will be defined in order to see the effects we propose.
Participants' respiration data will be objectively tracked using a wearable respiration
tracker device.

Inclusion Criteria:

- 18-65 years of age, able to provide their consent to be in the study, available and able
to participate in study activities, who can lie in supine, able to walk 15 feet, who have
no prior/current mind-body practice inducing breath awareness or training such as yoga,
meditation, Ta-Chi, Qi-Gong.

Exclusion Criteria:

- Inability to provide informed consent, MRI contraindications, need for muscle relaxants
or anti-anxiety drugs in order to tolerate MRI, history of neurological disorders, head
trauma with loss of consciousness, craniospinal disorders, spinal injury, sleep disorders,
allergic or respiratory disorders, major or uncontrolled psychiatric illness or major
depression, lung and heart problems, any condition requiring the use of medication that
acts on the brain like stimulants, sedatives current substance abuse issues, pregnancy or
nursing.
We found this trial at
1
site
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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from
Portland, OR
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