The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain, Post-Surgical Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/3/2019 |
| Start Date: | May 1, 2014 |
| End Date: | November 1, 2017 |
The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy: A Randomized Control Trial
The purpose of the study is to determine the efficacy of IV acetaminophen when administered
to neurosurgical patients at the beginning and end of their surgery. If the result is
improved pain control with less opioid consumption postoperatively, then those patients may
also experience less opioid related side effects such as nausea/vomiting, pruritus, and
sedation. While numerous other studies have failed to show a benefit of IV acetaminophen
after neurosurgical procedures, we are studying the administration of 1 g in two doses over
the course of the operation.
to neurosurgical patients at the beginning and end of their surgery. If the result is
improved pain control with less opioid consumption postoperatively, then those patients may
also experience less opioid related side effects such as nausea/vomiting, pruritus, and
sedation. While numerous other studies have failed to show a benefit of IV acetaminophen
after neurosurgical procedures, we are studying the administration of 1 g in two doses over
the course of the operation.
Inclusion Criteria:
- Patients with a diagnosis of bilateral moyamoya disease scheduled for bilateral
external-carotid to internal-carotid bypass surgery to be done in two stages.
Exclusion Criteria:
- Allergy or history of reaction to acetaminophen. Patients with liver disease. Anyone
not able to provide informed consent.
We found this trial at
1
site
Click here to add this to my saved trials
