Extinction Learning in Youth With Tourette Syndrome
| Status: | Recruiting |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 8 - 17 |
| Updated: | 3/6/2019 |
| Start Date: | February 28, 2019 |
| End Date: | July 1, 2023 |
| Contact: | Joey Essoe, PhD |
| Email: | essoe@jhmi.edu |
| Phone: | 443-287-7157 |
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral
treatment model of tics. Extinction learning and extinction recall are learning processes
implicated within this model, but have not been directly evaluated in youth with Tourette
syndrome (TS). This study examines extinction learning and extinction recall in youth with TS
using an experimental task. This study will also explore the relationship between extinction
processes (i.e., extinction learning and extinction recall) and treatment outcomes with
behavior therapy. Findings from this investigation will be used to update the behavioral
treatment model, which serves as the basis for evidence-based behavioral interventions.
treatment model of tics. Extinction learning and extinction recall are learning processes
implicated within this model, but have not been directly evaluated in youth with Tourette
syndrome (TS). This study examines extinction learning and extinction recall in youth with TS
using an experimental task. This study will also explore the relationship between extinction
processes (i.e., extinction learning and extinction recall) and treatment outcomes with
behavior therapy. Findings from this investigation will be used to update the behavioral
treatment model, which serves as the basis for evidence-based behavioral interventions.
Youth with TS will be eligible for participation if they meet the following inclusion
criteria:
- age 8-17 years (inclusive)
- have moderate tic severity or greater as evidenced by a YGTSS Total Tic Score greater
than 13 (>9 for youth with motor or vocal tics only)
- have not received more than 4 previous sessions of HRT
- be fluent in English.
- Medication free or on a stable dose of psychiatric medication for 8 weeks prior to
enrollment.
Exclusion criteria for youth with TS:
- An inability to complete rating scales
- Attend study visits.
We found this trial at
1
site
733 North Broadway
Baltimore, Maryland 21205
Baltimore, Maryland 21205
(410) 955-3182
Phone: 443-287-7157
Johns Hopkins University School of Medicine Johns Hopkins Medicine (JHM), headquartered in Baltimore, Maryland, is...
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