A Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate Cancer
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Prostate Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/31/2019 |
| Start Date: | April 1, 2019 |
| End Date: | August 4, 2021 |
| Contact: | Study Contact |
| Email: | JNJ.CT@sylogent.com |
| Phone: | 844-434-4210 |
Biomarker Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate Cancer
The purpose of this study is to evaluate the prevalence of 4 or more DNA-repair defects in a
population of men with metastatic Prostate Cancer (PC) and to use the variants reported to
assess biomarker eligibility for niraparib interventional studies.
population of men with metastatic Prostate Cancer (PC) and to use the variants reported to
assess biomarker eligibility for niraparib interventional studies.
Inclusion Criteria:
- Diagnosis of metastatic (Stage IV) prostate cancer (PC), confirmed by either biopsy of
a metastatic tumor site or history of localized disease supported by metastatic
disease on imaging studies (that is [i.e.], clearly noted in hospital/clinical
records)
- Signed Informed consent form (ICF)
- No condition for which, in the opinion of the investigator, participation would not be
in the best interest of the participant (for example [e.g.], compromise the
well-being) or that could prevent, limit, or confound the protocol-specified
assessments
- Willing to provide a saliva or blood sample for genomic analysis
We found this trial at
12
sites
Barbara Ann Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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University of Virginia The University of Virginia is distinctive among institutions of higher education. Founded...
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Duke Cancer Institute Leading-edge cancer care and research have been a hallmark of Duke Medicine...
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600 Highland Ave.
Madison, Wisconsin 53792
Madison, Wisconsin 53792
(608) 263-6400
University of Wisconsin Carbone Cancer Center UW Carbone Cancer Center holds the unique distinction of...
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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