Infrared Thermography in Finding Skin Lesions in Patients With Kaposi's Sarcoma
| Status: | Terminated |
|---|---|
| Conditions: | Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - 120 |
| Updated: | 3/22/2019 |
| Start Date: | October 3, 2005 |
| End Date: | March 21, 2006 |
Ultra-Sensitive, Infra-Red Thermographic Analysis of Kaposi's Sarcoma Skin Lesions
RATIONALE: Diagnostic procedures, such as infrared thermography, may help find Kaposi's
sarcoma and learn the extent of disease.
PURPOSE: This clinical trial is studying how well infrared thermography finds skin lesions in
patients with Kaposi's sarcoma.
sarcoma and learn the extent of disease.
PURPOSE: This clinical trial is studying how well infrared thermography finds skin lesions in
patients with Kaposi's sarcoma.
OBJECTIVES:
Primary
- Compare ultra-sensitive infrared thermographic images with visible light digital
photographic images and clinical dermatologic examination as methods of measuring
cutaneous lesions in patients with Kaposi's sarcoma (KS).
Secondary
- Compare differences in modulation of temperature detected in KS skin lesions with
non-involved skin of the same patient and with normal skin of healthy volunteers by
sequential imaging using the infrared thermographic camera.
OUTLINE: This is a controlled, pilot study.
Patients undergo clinical assessment followed by simultaneous digital photographic camera
imaging and high-resolution infrared thermographic camera imaging of designated normal skin
areas and selected marker lesions. Before imaging, a metal bar chilled to 0º C, 10º C, and
25º C is applied to the lesions and designated normal skin areas for up to 90 seconds.
Healthy volunteers (controls) undergo the same procedure as for the patient except only
designated normal skin areas are used.
PROJECTED ACCRUAL: A total of 20 patients and 10 healthy volunteers (controls) will be
accrued for this study.
Primary
- Compare ultra-sensitive infrared thermographic images with visible light digital
photographic images and clinical dermatologic examination as methods of measuring
cutaneous lesions in patients with Kaposi's sarcoma (KS).
Secondary
- Compare differences in modulation of temperature detected in KS skin lesions with
non-involved skin of the same patient and with normal skin of healthy volunteers by
sequential imaging using the infrared thermographic camera.
OUTLINE: This is a controlled, pilot study.
Patients undergo clinical assessment followed by simultaneous digital photographic camera
imaging and high-resolution infrared thermographic camera imaging of designated normal skin
areas and selected marker lesions. Before imaging, a metal bar chilled to 0º C, 10º C, and
25º C is applied to the lesions and designated normal skin areas for up to 90 seconds.
Healthy volunteers (controls) undergo the same procedure as for the patient except only
designated normal skin areas are used.
PROJECTED ACCRUAL: A total of 20 patients and 10 healthy volunteers (controls) will be
accrued for this study.
DISEASE CHARACTERISTICS:
- Meets 1 of the following criteria:
- Histologically confirmed cutaneous Kaposi's sarcoma (KS)
- At least one skin lesion accessible for imaging
- HIV positivity with proven cutaneous KS and concurrent visceral or mucous
membrane involvement allowed
- Healthy volunteer (regardless of HIV status) (control)
PATIENT CHARACTERISTICS:
Performance status
- Not specified
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
Other
- Pregnancy allowed
PRIOR CONCURRENT THERAPY:
- Prior topical, intralesional, or systemic treatment allowed
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins The name Johns Hopkins has become synonymous...
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