Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome
| Status: | Completed |
|---|---|
| Conditions: | Bronchitis, Hospital, Women's Studies |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases, Other, Reproductive |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 3/24/2019 |
| Start Date: | January 1991 |
| End Date: | January 1992 |
Efficacy and Safety of Exosurf Neonatal and Survanta for the Treatment of Respiratory Distress Syndrome
The purpose of this study is to compare the efficacy of two surfactants, Exosurf Neonatal
(Burroughs Wellcome Co.) and Survanta (Ross Laboratories), for the treatment of neonatal
respiratory distress syndrome.
(Burroughs Wellcome Co.) and Survanta (Ross Laboratories), for the treatment of neonatal
respiratory distress syndrome.
The NICHD Neonatal Research Network conducted a randomized trial at 11 centers comparing the
efficacy of two surfactants -- Exosurf Neonatal (Burroughs Wellcome Co.) and Survanta (Ross
Laboratories) -- for the treatment of neonatal respiratory distress syndrome. Newborn infants
with birth weights of 501-1500g with respiratory distress syndrome who were receiving
assisted ventilation with 30% oxygen or more within 6 hours of birth were enrolled between
January 1991 and January 1992. Infants were randomly assigned to receive up to four
intratracheal doses of either Exosurf Neonatal or Survanta.
efficacy of two surfactants -- Exosurf Neonatal (Burroughs Wellcome Co.) and Survanta (Ross
Laboratories) -- for the treatment of neonatal respiratory distress syndrome. Newborn infants
with birth weights of 501-1500g with respiratory distress syndrome who were receiving
assisted ventilation with 30% oxygen or more within 6 hours of birth were enrolled between
January 1991 and January 1992. Infants were randomly assigned to receive up to four
intratracheal doses of either Exosurf Neonatal or Survanta.
Inclusion Criteria:
- Newborn infants weighing 501 to 1500 gm with respiratory distress syndrome were
receiving assisted ventilation with 30% oxygen or more
Exclusion Criteria:
- Less than 6 hours of age
We found this trial at
13
sites
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Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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University of Vermont The University of Vermont combines faculty-student relationships most commonly found in a...
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Univ of Texas, Southwestern Med Ctr of Dallas The story of UT Southwestern Medical Center...
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Wayne State University Founded in 1868, Wayne State University is a nationally recognized metropolitan research...
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Indiana University INDIANA UNIVERSITY is a major multi-campus public research institution, grounded in the liberal...
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University of Miami A private research university with more than 15,000 students from around the...
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University of New Mexico Founded in 1889 as New Mexico’s flagship institution, the University of...
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Yale University Yale's roots can be traced back to the 1640s, when colonial clergymen led...
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