Study of Ketorolac Versus Opioid for Pain After Endoscopy
| Status: | Recruiting |
|---|---|
| Conditions: | Nephrology, Nephrology, Nephrology |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - 70 |
| Updated: | 3/27/2019 |
| Start Date: | October 13, 2017 |
| End Date: | July 2021 |
| Contact: | Naveen Kachroo, MD |
| Email: | kachron@ccf.org |
| Phone: | 216-973-5227 |
Study of Ketorolac Versus Opioid for Pain After Endoscopy (SKOPE): A Double-blinded Randomized Control Trial Comparing Outpatient Analgesic Efficacy of NSAIDs and Opioids in Patients Undergoing Ureteroscopy for Kidney Stones
A double blind randomized controlled trial designed to compare pain control and safety with
ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy
for treatment of urinary stones. Patients are followed for five days after their surgery as
they record their pain scores, medication utilization, and stent related symptoms.
ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy
for treatment of urinary stones. Patients are followed for five days after their surgery as
they record their pain scores, medication utilization, and stent related symptoms.
Inclusion Criteria:
- Patients with kidney or ureteral stones confirmed on imaging (CT of the abdomen
pelvis) and who elect for definitive treatment via unilateral ureteroscopy at one of
two hospital sites within a tertiary care institution
- Patients who post-operatively receive a unilateral ureteral stent
- Capable of giving informed consent
- Capable and willing to fulfill requirements of the study
Exclusion Criteria:
- Active or history of peptic ulcer disease, gastrointestinal bleeding or perforation
- History of coronary artery bypass graft surgery
- History of a bleeding disorder
- GFR less than 60 mL/min/1.73m2 (MDRD equation)
- Chronic use of opioid or other pain medication including NSAIDs (greater than 12
weeks)
- Known allergy to either ketorolac or oxycodone
- Known or suspected pregnancy
- Solitary kidney
- Patients taking anticoagulant medication or antiplatelet medication (e.g. warfarin,
clopidogrel, pradaxa, rivaroxaban, apixaban etc).
- Inability to give informed consent or unable to meet requirements of the study for any
reason
We found this trial at
1
site
2049 E 100th St
Cleveland, Ohio 44106
Cleveland, Ohio 44106
(216) 444-2200
Principal Investigator: Sriharan Sivalingam, MD
Phone: 513-255-6699
Cleveland Clinic Foundation The Cleveland Clinic (formally known as The Cleveland Clinic Foundation) is a...
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