Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1

Subjects will be expected to attend 3 study visits and wear study lenses for approximately 14
- 20 days (7 - 10 days for each product).

Inclusion Criteria:

- Able to understand and sign an Informed Consent Form that has been approved by an
Institutional Review Board.

- Willing and able to attend all scheduled study visits as required per protocol.

- Successful wear of spherical soft contact lenses for distance correction in both eyes
during the past 3 months for a minimum of 5 days per week and 8 hours per day.

- Manifest cylinder of ≤ 0.75 diopter (D) in each eye.

- Best corrected visual acuity (VA) of 20/25 or better in each eye.

- Able to wear contact lenses within a range of sphere power from -1.00 to -6.00 D (0.25
D steps) and VA of 20/25 or better in each eye with fitting set lenses.

Exclusion Criteria:

- Any anterior segment infection, inflammation, or abnormality or disease (including
systemic) that contraindicates contact lens wear.

- Any use of systemic or ocular medications for which contact lens wear could be
contraindicated.

- History of ocular or intraocular surgery, including refractive surgery and/or
irregular cornea.

- Biomicroscopy findings at baseline that are moderate (grade 3) or higher and/or
corneal vascularization that is mild (grade-2) or higher.

- Current or history of pathologically dry eye in either eye that would preclude contact
lens wear.

- Eye injury in either eye within 12 weeks immediately prior to enrollment for this
trial.

- Wearing habitual contact lenses in an extended wear modality (routinely sleeping in
lenses for at least 1 night per week) over the last 3 months prior to enrollment.

- Any use of topical ocular medications and artificial tear or rewetting drops that
would require instillation during contact lens wear.

- Previous or current habitual wearers of ACUVUE® MOIST or DAILIES TOTAL1® contact
lenses.

Other protocol-specified criteria may apply.