Dynamic Contrast Enhanced Computed Tomography to Assess Radiation Therapy in Liver Cancer Patients



Status:Not yet recruiting
Conditions:Liver Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - 100
Updated:3/29/2019
Start Date:May 2019
End Date:January 2021
Contact:Tess Santangelo
Email:tess.santangelo@ucdenver.edu
Phone:720-848-9398

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Trial Summary
Trial Overview
Inclusion Criteria

Pilot Study of Dynamic Contrast Enhanced Computed Tomography (DCE-CT) Imaging for the Assessment of Radiation Therapy Outcome for Liver Cancer Patients

This is a pilot study that uses a standard of care technique, Stereotactic Body Radiation
Therapy (SBRT), in combination with Dynamic Contrast Enhanced Computed Tomography (DCE-CT) to
determine if perfusion changes from SBRT of liver cancer may be used for outcome assessment
and prediction of prognosis.

Patients will undergo standard of care SBRT while also receiving DCE-CT, also known as
perfusion CT, pre-treatment, 6 hours post-treatment and 6 weeks post-treatment.

Inclusion Criteria:

1. Provision to sign and date the consent form

2. Stated willingness to comply with all study procedures and be available for the
duration of the study

3. Be a Male or Female aged 18-100

4. Diagnosed with Liver HCC or metastases

5. Must be receiving or will plan to receive SBRT for Liver HCC or metastases

Exclusion Criteria:

1. Allergy to iodine contrast

2. CT with contrast not offered as a Standard of Care

3. Pregnant women
We found this trial at
1
site
University of Colorado Denver
13001 E. 17th Pl
Aurora, Colorado 80045
303-724-5000
Principal Investigator: Moyed Miften, PhD
Phone: 720-848-9398
University of Colorado Denver The University of Colorado Denver | Anschutz Medical Campus provides a...
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