The Effect of Intravenous Lidocaine on Allodynia

Clinicians use lidocaine intravenously in a fashion that suggests that it might have
analgesic effects. Therefore, we test the hypothesis that lidocaine reduces pain intensity
in response to experimental pain.

Inclusion Criteria:

- Chronic Regional Pain Syndrome diagnostic criteria by the Work Safe BC. vi

Exclusion Criteria:

- History of Substance abuse

- Other Medications: CRPS patients are expected to be treated for chronic pain, whether
the current treatment regimen interferes with sensory motor testing will be
determined on a case by case basis.

- Coronary Artery Disease (CAD): unstable

- Congestive Heart Failure (CHF): unstable

- Heart Arrhythmia: symptomatic

- Chronic Obstructive Pulmonary Disease (COPD)

- Lidocaine Allergy

- Diagnostic and Statistical Manual of Mental Disorders (Rev IV): Axis I: Common Axis I
disorders include depression, anxiety disorders, bipolar disorder, ADHD, and
schizophrenia. Axis II: borderline personality disorder, schizotypal personality
disorder, antisocial personality disorder, and mild mental retardation.

- Presence of Contraindications for MRI

- Presence of electronically, magnetically, and mechanically activated implants

- Electronically, magnetically, and mechanically activated implants

- Ferromagnetic or electronically operated active devices like automatic cardioverter
defibrillators

- Cardiac pacemakers

- Metallic splinters in the eye

- Ferromagnetic haemostatic clips in the central nervous system (CNS)

- Claustrophobia

- Pregnancy