Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients



Status:Terminated
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:50 - 89
Updated:4/21/2016
Start Date:June 2008
End Date:August 2013

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy And Safety Trial Of Bapineuzumab (Aab-001, Eln115727) In Subjects With Mild to Moderate Alzheimer Disease Who Are Apolipoprotein E 4 Non-carriers

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in
patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab
or placebo. Each patient's participation will last approximately 1.5 years.


Inclusion Criteria:

- Diagnosis of probable Alzheimer Disease (AD), with Mini Mental State Examination
(MMSE) score of 16-26, and brain magnetic resonance imaging (MRI) consistent with the
diagnosis of AD

- Concurrent use of cholinesterase inhibitor or memantine allowed, if stable

- Caregiver will participate and be able to attend clinic visits with patient

Exclusion Criteria:

- Significant neurological disease other than AD

- Major psychiatric disorder

- Contraindication to undergo brain MRI [e.g., pacemaker, cerebrospinal fluid (CSF)
shunt, or foreign metal objects in the body]

- Women of childbearing potential
We found this trial at
161
sites
ActivMed Practices and Research
Haverhill, Massachusetts 01830
?
mi
from
Haverhill, MA
Click here to add this to my saved trials
Comprehensive Clinical Research
175 Cross Keys Rd.
Berlin, New Jersey 08009
856-753-7335
?
mi
from
Berlin, NJ
Click here to add this to my saved trials
University of Alabama at Birmingham
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
?
mi
from
Boston, MA
Click here to add this to my saved trials
Brigham and Women's Hosp
75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
?
mi
from
Boston, MA
Click here to add this to my saved trials
Alpine Clinical Research Center
1000 Alpine
Boulder, Colorado 80304
303-443-7229
?
mi
from
Boulder, CO
Click here to add this to my saved trials
University of North Texas Health Science Center
3500 Camp Bowie Boulevard
Fort Worth, Texas 76107
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
MD Clinical
911 E. Hallandale Beach Blvd
Hallandale Beach, Florida 33009
954-455-5757
?
mi
from
Hallandale Beach, FL
Click here to add this to my saved trials
Renstar Medical Research
104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
?
mi
from
Ocala, FL
Click here to add this to my saved trials
Compass Research LLC
100 West Gore St # 202
Orlando, Florida 32806
(407) 426-9299
Compass Research LLC Compass Research is a clinical research company dedicated to testing new medications...
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Hospital of the University of Pennsylvania
3400 Spruce St
Philadelphia, Pennsylvania 19104
 (215) 662-4000
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials
Innovative Clinical Trials
5430 Fredericksburg Road
San Antonio, Texas 78229
210-377-2873
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Integra Clinical Research
3603 Paesanos Parkway
San Antonio, Texas 78231
210-614-4884
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Stedman Clinical Trials
3212 Cove Bend Drive
Tampa, Florida 33613
?
mi
from
Tampa, FL
Click here to add this to my saved trials
Neurology & Neuroscience Center of Ohio
1000 Regency Court
Toledo, Ohio 43623
419-841-7369
?
mi
from
Toledo, OH
Click here to add this to my saved trials
Chase Medical Research, LLC
500 Chase Parkway
Waterbury, Connecticut 06708
203-419-4420
?
mi
from
Waterbury, CT
Click here to add this to my saved trials
Abington Memorial Hospital
1200 Old York Road
Abington, Pennsylvania 19001
(215) 481–2000
Abington Memorial Hospital Abington Memorial Hospital (AMH) is a 665-bed, regional referral center and teaching...
?
mi
from
Abington, PA
Click here to add this to my saved trials
Abington Neurological Associates
Abington, Pennsylvania 19001
?
mi
from
Abington, PA
Click here to add this to my saved trials
University of Michigan Health System
1500 E Medical Center Dr
Ann Arbor, Michigan 48109
(734) 936-4000
University of Michigan Health System The University of Michigan is home to one of the...
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
University of Michigan Hospital
Ann Arbor, Michigan 48109
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Clinical Study Center of Asheville, LLC
Asheville, North Carolina 28803
?
mi
from
Asheville, NC
Click here to add this to my saved trials
NeuroTrials Research, Incorporated
Atlanta, Georgia 30342
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
JEM Research Institute
Atlantis, Florida 33462
?
mi
from
Atlantis, FL
Click here to add this to my saved trials
Medical Specialists of the Palm Beaches
Atlantis, Florida 33462
?
mi
from
Atlantis, FL
Click here to add this to my saved trials
Austin Infusion Centers
Austin, Texas 78756
?
mi
from
Austin, TX
Click here to add this to my saved trials
Senior Adults Specialty Research
Austin, Texas 78757
?
mi
from
Austin, TX
Click here to add this to my saved trials
Southwestern Vermont Healthcare
Bennington, Vermont 05201
?
mi
from
Bennington, VT
Click here to add this to my saved trials
The Memory Clinic
Bennington, Vermont 05201
?
mi
from
Bennington, VT
Click here to add this to my saved trials
Foers Medical Arts Pharmacy
Bethesda, Maryland 20814
?
mi
from
Bethesda, MD
Click here to add this to my saved trials
Bringham and Women's Hospital
Boston, Massachusetts 02115
?
mi
from
Boston, MA
Click here to add this to my saved trials
General Clinical Research Center
Boston, Massachusetts 02118
?
mi
from
Boston, MA
Click here to add this to my saved trials
Boston University
One Silber Way
Boston, Massachusetts 02215
(617) 353-2000
Boston University Boston University is no small operation . With over 33,000 undergraduate and graduate...
?
mi
from
Boston, MA
Click here to add this to my saved trials
IDS Pharmacy
Boston, Massachusetts 02118
?
mi
from
Boston, MA
Click here to add this to my saved trials
Pacific Medical Centers
Bothell, Washington 98021
?
mi
from
Bothell, WA
Click here to add this to my saved trials
Associated Neurologists, PC
Boulder, Colorado 80304
?
mi
from
Boulder, CO
Click here to add this to my saved trials
Bradenton Research Center, Incorporated
Bradenton, Florida 34205
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
Northeast Radiology
Brewster, New York 10509
?
mi
from
Brewster, NY
Click here to add this to my saved trials
Cemic University Hospital
Buenos Aires,
?
mi
from
Buenos Aires,
Click here to add this to my saved trials
Medical University of South Carolina Hospitals and Clinics
Charleston, South Carolina 29425
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Medical University of South Carolina Investigational Drug Service
Charleston, South Carolina 29425
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Alzheimer's Memory Center
Charlotte, North Carolina 28211
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
University of Virginia Neurology
Charlottesville, Virginia 22903
?
mi
from
Charlottesville, VA
Click here to add this to my saved trials
University Of Virginia General Clinical Research Center
Charlottesville, Virginia 22908
?
mi
from
Charlottesville, VA
Click here to add this to my saved trials
University of Viriginia Investigational Pharmacy
Charlottesville, Virginia 22908
?
mi
from
Charlottesville, VA
Click here to add this to my saved trials
Columbus Diagnostic Center (MRI)
Columbus, Georgia 31901
?
mi
from
Columbus, GA
Click here to add this to my saved trials
Medical Research and Health Education Foundation, Incorporated
Columbus, Georgia 31909
?
mi
from
Columbus, GA
Click here to add this to my saved trials
Ohio State University Imaging at Martha Morehouse
Columbus, Ohio 43210
?
mi
from
Columbus, OH
Click here to add this to my saved trials
The Ohio State University Hospitals Clinic
Columbus, Ohio 43210
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Ohio State University Medical Center
Columbus, Ohio 43210
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Ohio State University
281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Neurology Clinic, PC
Cordova, Tennessee 38018
?
mi
from
Cordova, TN
Click here to add this to my saved trials
ATP Clinical Research, Incorporated
Costa Mesa, California 92626
?
mi
from
Costa Mesa, CA
Click here to add this to my saved trials
Texas Neurology, PA
Dallas, Texas 75214
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Associated Neurologists, P.C.
Danbury, Connecticut 06810
?
mi
from
Danbury, CT
Click here to add this to my saved trials
Dekalb Neurology Associates, LLC/NeuroStudies.net, LLC
Decatur, Georgia 30033
?
mi
from
Decatur, GA
Click here to add this to my saved trials
NeuroStudies.net
Decatur, Georgia 30033
?
mi
from
Decatur, GA
Click here to add this to my saved trials
North Broward Medical Center
Deerfield Beach, Florida 33064
?
mi
from
Deerfield Beach, FL
Click here to add this to my saved trials
Brain Matters Research
Delray Beach, Florida 33445
?
mi
from
Delray Beach, FL
Click here to add this to my saved trials
Mile High Research Center
Denver, Colorado 80218
?
mi
from
Denver, CO
Click here to add this to my saved trials
Michigan State University
East Lansing, Michigan 48824
?
mi
from
East Lansing, MI
Click here to add this to my saved trials
Rhode Island Mood & Memory Research Institute
East Providence, Rhode Island 02914
?
mi
from
East Providence, RI
Click here to add this to my saved trials
Memory Enhancement Center of America, Inc.
Eatontown, New Jersey 07724
?
mi
from
Eatontown, NJ
Click here to add this to my saved trials
Alexian Brothers Medical Center
Elk Grove Village, Illinois 60007
?
mi
from
Elk Grove Village, IL
Click here to add this to my saved trials
Alexian Brothers Neurosciences Institute
Elk Grove Village, Illinois 60007
?
mi
from
Elk Grove Village, IL
Click here to add this to my saved trials
Elkhart Clinic, LLC
303 S Nappanee St
Elkhart, Indiana 46514
(574) 296-3200
Elkhart Clinic, LLC Informed participation in the management of your health care maximizes your Elkhart...
?
mi
from
Elkhart, IN
Click here to add this to my saved trials
Pharmacology Research Institute
Encino, California 91316
?
mi
from
Encino, CA
Click here to add this to my saved trials
Associated Neurologists of Southern Connecticut, PC
Fairfield, Connecticut 06824
?
mi
from
Fairfield, CT
Click here to add this to my saved trials
Marty's Pharmacy
Flowood, Mississippi 39232
?
mi
from
Flowood, MS
Click here to add this to my saved trials
Precise Research Centers
Flowood, Mississippi 39232
?
mi
from
Flowood, MS
Click here to add this to my saved trials
Neurologic Consultants, PA
Fort Lauderdale, Florida 33308
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
Margolin Brain Institute
Fresno, California 93720
?
mi
from
Fresno, CA
Click here to add this to my saved trials
Dedicated Clinical Research
Goodyear, Arizona 85395
?
mi
from
Goodyear, AZ
Click here to add this to my saved trials
Advanced Neurology Specialists
Great Falls, Montana 59405
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
Spectrum Home Solutions
Great Falls, Montana 59405
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
Bendheim Cancer Center
Greenwich, Connecticut 06830
?
mi
from
Greenwich, CT
Click here to add this to my saved trials
Center for Healthy Aging
Greenwich, Connecticut 06830
?
mi
from
Greenwich, CT
Click here to add this to my saved trials
Radiant Research, Incorporated
Greer, South Carolina 29651
?
mi
from
Greer, SC
Click here to add this to my saved trials
Hattiesburg Clinic
Hattiesburg, Mississippi 39401
?
mi
from
Hattiesburg, MS
Click here to add this to my saved trials
Clinical Trials of America, Incorporated
Hickory, North Carolina 28601
?
mi
from
Hickory, NC
Click here to add this to my saved trials
The Compounding Pharmacy
Hickory, North Carolina 28602
?
mi
from
Hickory, NC
Click here to add this to my saved trials
The Clinical Trial Center, LLC
Jenkintown, Pennsylvania 19046
?
mi
from
Jenkintown, PA
Click here to add this to my saved trials
The Center for Pharmaceutical Research, P.C.
Kansas City, Missouri 64114
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Infusion Care Pharmacey
Laguna Hills, California 92653
?
mi
from
Laguna Hills, CA
Click here to add this to my saved trials
Senior Clinical Trials, Incorporated
Laguna Hills, California 92653
?
mi
from
Laguna Hills, CA
Click here to add this to my saved trials
Lake Charles Clinical Trials LLC
Lake Charles, Louisiana 70601
?
mi
from
Lake Charles, LA
Click here to add this to my saved trials
Michigan State University
409 West Circle Drive
Lansing, Michigan 48910
?
mi
from
Lansing, MI
Click here to add this to my saved trials
Neurostudies.net
Lawerenceville, Georgia 30045
?
mi
from
Lawerenceville, GA
Click here to add this to my saved trials
Neurostudies.net
Lawrenceville, Georgia 30046
?
mi
from
Lawrenceville, GA
Click here to add this to my saved trials
Clinical Trials, Inc.
Little Rock, Arkansas 72205
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Neurological Care of Central New York
Liverpool, New York 13088
?
mi
from
Liverpool, NY
Click here to add this to my saved trials
Faculty Physicians and Surgeons of Loma Linda University School of Medicine
Loma Linda, California 92354
?
mi
from
Loma Linda, CA
Click here to add this to my saved trials
Loma Linda University Medical Center
11234 Anderson St
Loma Linda, California 92354
(909) 558-4000
Loma Linda University Medical Center An outgrowth of the original Sanitarium on the hill in...
?
mi
from
Loma Linda, CA
Click here to add this to my saved trials
Collaborative Neuroscience Network, Inc.
Long Beach, California 90806
?
mi
from
Long Beach, CA
Click here to add this to my saved trials
Pharmacology Research Institute
Los Alamitos, California 90720
?
mi
from
Los Alamitos, CA
Click here to add this to my saved trials
Alzheimer's Research Corporation
Manchester, New Jersey 08759
?
mi
from
Manchester, NJ
Click here to add this to my saved trials
Psychology Associates
Mishawaka, Indiana 46545
?
mi
from
Mishawaka, IN
Click here to add this to my saved trials
The Institute for Neurodegenerative Disorders
New Haven, Connecticut 06510
?
mi
from
New Haven, CT
Click here to add this to my saved trials
Yale University School of Medicine
333 Cedar St
New Haven, Connecticut 06504
(203) 432-4771
Yale University School of Medicine Founded in 1810, the Yale School of Medicine is a...
?
mi
from
New Haven, CT
Click here to add this to my saved trials
Yale-New Haven Hospital
20 York St, N20 York St,
New Haven, Connecticut 06520
(203) 688-4242
Yale-New Haven Hospital Relying on the skill and expertise of more than 4,500 university and...
?
mi
from
New Haven, CT
Click here to add this to my saved trials
Norman S. Werdiger, MD
New Haven, Connecticut 06519
?
mi
from
New Haven, CT
Click here to add this to my saved trials
Institutional Review Board / Ethics Committee
New Haven, Connecticut 06520
?
mi
from
New Haven, CT
Click here to add this to my saved trials