New Clinical Trials for Bipolar Disorder

Figure represents symptoms of bipolar disorderClinical trials for bipolar disorder are helping to improve the diagnosis and treatment of this medical condition in both children and adults. Through new clinical studies, specialists are gaining a better understanding of the biological basis for bipolar disorder, which allows them to develop safer and more effective treatments for younger patients. Recent bipolar clinical trials have identified links between specific genetic profiles and responses to certain antidepressant drugs used to treat this condition.

If you are interested in enrolling in a bipolar disorder clinical trial, then you may be among the first to receive an experimental treatment not available anywhere else. It should be noted that since these therapies are still experimental, there is no guarantee that it will produce a beneficial effect. If conventional therapies have proven unsuccessful for your condition, you may want to ask your doctor about participating in a bipolar clinical trial.

What is Bipolar Disorder?

Bipolar disorder, also known as manic depression, produces acute mood swings that can include periods of manic emotional highs and extremely depressed lows. The onset of bipolar symptoms usually occur during the late adolescence or early adulthood, although it is possible for children to develop this medical condition. It is caused by an imbalance of chemicals within the brain responsible for regulating the emotions. Specialists believe that it results from a complex set of genetic and environmental factors.

Aside from the severe fluctuations in mood and energy levels, the symptoms of bipolar disorder can make it difficult for patients to maintain relationships or perform well at school or work. Fortunately, there are a number of treatments and therapies which can help them gain some measure of control over their symptoms. The most commonly prescribed treatments for bipolar disorder include a mixture of medications and psychological counseling (psychotherapy).

Bipolar Disorder Treatment

There is no cure available for bipolar disorder, which means that patients will require lifelong treatment, even during the times when they feel emotionally stable. Most patients will be connected with a psychiatrist who is expertly trained in treating this medical condition, and they will guide them through their treatment plan. Depending on the severity, some bipolar patients will require a full medical team that could include social workers, psychologists, and psychiatric nurses. In addition to prescribed medications and psychotherapy, patients can also get help from specific support groups.

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We've found
453 Bipolar Disorder
clinical trials

Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Asheville, NC
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Dallas, TX
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Decatur, GA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Denver, CO
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Las Vegas, NV
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Milwaukee, WI
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Minneapolis, MN
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Orlando, FL
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Temple, TX
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Tucson, AZ
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Neurology, Psychiatry / Psychology Clinical Trial
The Family VOICE Study
Status: Enrolling
Updated: 12/8/2015
mi
from
Baltimore, MD
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Psychiatry / Psychology Clinical Trial
Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
Status: Enrolling
Updated: 7/1/2013
mi
from
Boston, MA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Gainesville, FL
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Oklahoma City, OK
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Neurology, Psychiatry / Psychology Clinical Trial
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Bronx, NY
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Atlanta, GA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Baltimore, MD
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study
Status: Enrolling
Updated: 8/28/2017
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
Role Functioning Changes NOS
Status: Enrolling, Phase
Updated: 3/30/2018
mi
from
Chicago, IL
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Psychiatry / Psychology Clinical Trial
Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Miami, FL
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BIPOLAR DISORDER Clinical Trial
DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder
Status: Enrolling, Phase IV
Updated: 1/6/2016
mi
from
Baltimore, MD
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BIPOLAR DISORDER Clinical Trial
Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs
Status: Enrolling, Phase IV
Updated: 6/1/2016
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Dallas, TX
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Dallas, TX
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Oklahoma City, OK
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Rochester, NY
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BIPOLAR DISORDER Clinical Trial
A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Saint Louis, MO
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness
Status: Enrolling
Updated: 3/13/2018
mi
from
Chicago, IL
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Psychiatry / Psychology Clinical Trial
The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders
Status: Enrolling, Phase
Updated: 4/19/2018
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Atlanta, GA
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Desoto, TX
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Flowood, MS
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Kansas City, MO
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Lauderhill, FL
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Psychiatry / Psychology Clinical Trial
Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Oceanside, CA
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Endocrinology, Psychiatry / Psychology Clinical Trial
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Austin, TX
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Endocrinology, Psychiatry / Psychology Clinical Trial
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Houston, TX
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Endocrinology, Psychiatry / Psychology Clinical Trial
Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
National City, CA
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Austin, TX
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Berlin, NJ
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Farmington, CT
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Glendale, CA
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Little Rock, AR
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Little Rock, AR
Click here to add this to my saved trials
Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Oakland, CA
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Psychiatry / Psychology Clinical Trial
A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Raleigh, NC
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Atlanta, GA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Atlanta, GA
Click here to add this to my saved trials
Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Charlotte, NC
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Culver City, CA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Panorama City, CA
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Psychiatry / Psychology Clinical Trial
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Shreveport, LA
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Endocrinology, Psychiatry / Psychology Clinical Trial
Saxenda® in Obese or Overweight Patients With Stable Bipolar Disorder (Investigator Initiated)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Mason, OH
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Psychiatry / Psychology Clinical Trial
Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Rochester, NY
Click here to add this to my saved trials
BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Smyrna, GA
Click here to add this to my saved trials
BIPOLAR DISORDER Clinical Trial
Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Wildomar, CA
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Psychiatry / Psychology Clinical Trial
A Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disorder
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Garden Grove, CA
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Psychiatry / Psychology Clinical Trial
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Bethesda, MD
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BIPOLAR DISORDER Clinical Trial
Impact of Pregnancy and the Postpartum Period on Women With Bipolar Disorder
Status: Enrolling, Phase I
Updated: 8/3/2009
mi
from
Boston, MA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
Status: Enrolling, Phase I, II
Updated: 11/1/2010
mi
from
Irvine, CA
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Psychiatry / Psychology Clinical Trial
National Pregnancy Registry for Atypical Antipsychotics
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Boston, MA
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Early Intervention for Youth at Risk for Bipolar Disorder
Status: Enrolling, Phase II, III
Updated: 2/17/2014
mi
from
Boulder, CO
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Neurology, Psychiatry / Psychology, Other Clinical Trial
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
Status: Enrolling
Updated: 1/16/2018
mi
from
East Providence, RI
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Psychiatry / Psychology Clinical Trial
Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder
Status: Enrolling
Updated: 10/29/2015
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Boston, MA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Houston, TX
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Madison, WI
Click here to add this to my saved trials
Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Palo Alto, CA
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Psychiatry / Psychology Clinical Trial
Lithium for Suicidal Behavior in Mood Disorders
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Salt Lake City, UT
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Psychiatry / Psychology Clinical Trial
Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental Illness
Status: Enrolling, Phase III
Updated: 1/10/2014
mi
from
San Diego, CA
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BIPOLAR DISORDER Clinical Trial
Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder-Not Otherwise Specified
Status: Enrolling
Updated: 3/20/2014
mi
from
Palo Alto, CA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Baltimore, MD
Click here to add this to my saved trials
BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Boca Raton, FL
Click here to add this to my saved trials
BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Charlottesville, VA
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Garfield Heights, OH
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BIPOLAR DISORDER Clinical Trial
Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Marlton, NJ
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