Children's Hospital of Philadelphia
Since its start in 1855 as the nation's first hospital devoted exclusively to caring for children, The Children's Hospital of Philadelphia has been the birthplace for many dramatic firsts in pediatric medicine. The Hospital has fostered medical discoveries and innovations that have improved pediatric healthcare and saved countless children’s lives. Over 150 years of innovation and service to our patients, their families and our community, reflect an ongoing commitment to exceptional patient care.
We've found
402 trials
at this facility
Biliary Atresia Clinical Trial
Updated: 12/31/1969
Biliary Atresia Study in Infants and Children
Status: Enrolling,
Phase
Updated: 12/31/1969
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Endocrinology Clinical Trial
Updated: 12/31/1969
PKUDOS: Phenylketonuria (PKU) Demographic, Outcomes, and Safety Registry
Status: Enrolling,
Phase
Updated: 12/31/1969
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Congenital Hyperinsulinism Clinical Trial
Updated: 12/31/1969
Effect of Exendin-(9-39) On Glucose Requirements To Maintain Euglycemia
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Hematology, Oncology Clinical Trial
Updated: 12/31/1969
Study of Kidney Tumors in Younger Patients
Status: Enrolling,
Phase
Updated: 12/31/1969
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Hematology, Oncology Clinical Trial
Updated: 10/11/2012
Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
Status: Enrolling
Updated: 10/11/2012
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Endocrinology, Hematology, Immunology / Infectious Diseases, Oncology, Pharmacology / Toxicology, Reproductive Clinical Trial
Updated: 12/31/1969
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases Clinical Trial
Updated: 12/31/1969
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 7/22/2013
Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
Status: Enrolling
Updated: 7/22/2013
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Immunology / Infectious Diseases, Ophthalmology, Other, Reproductive Clinical Trial
Updated: 12/31/1969
Natural History Study of SCID Disorders
Status: Enrolling,
Phase
Updated: 12/31/1969
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Charcot Marie Tooth Disease Clinical Trial
Updated: 12/31/1969
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Status: Enrolling,
Phase
Updated: 12/31/1969
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Congenital Heart Defects Clinical Trial
Updated: 12/31/1969
Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Nephrology / Urology Clinical Trial
Updated: 12/31/1969
Nephrotic Syndrome Study Network
Status: Enrolling,
Phase
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 10/28/2015
Improving Medication Adherence in Pediatric Inflammatory Bowel Disease
Status: Enrolling,
Phase
III
Updated: 10/28/2015
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Gastroenterology, Reproductive Clinical Trial
Updated: 1/30/2017
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Status: Enrolling
Updated: 1/30/2017
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Injury of Anterior Cruciate Ligament Clinical Trial
Updated: 7/30/2014
Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Status: Enrolling,
Phase
III
Updated: 7/30/2014
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Oncology, Other Clinical Trial
Updated: 12/31/1969
Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 in Children and Adults
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Acute Arterial Ischemic Stroke Clinical Trial
Updated: 12/31/1969
Optical Measurement of Cerebral Hemodynamics in Children With Acute Arterial Ischemic Stroke
Status: Enrolling,
Phase
Updated: 12/31/1969
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Gastroenterology, Neurology, Otolaryngology, Pharmacology / Toxicology Clinical Trial
Updated: 12/31/1969
Molecular Basis of Food Allergy
Status: Enrolling,
Phase
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Brain Concussion Clinical Trial
Updated: 12/31/1969
BCAA's in Concussion
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/22/2015
Coagulation and Fibrinolysis in Pediatric Insulin Titration Trial (CAF-PINT)
Status: Enrolling
Updated: 12/22/2015
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Cardiology / Vascular Diseases Clinical Trial
Updated: 12/31/1969
Randomized Trial of Maternal Progesterone Therapy
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Obstructive Sleep Apnea Syndrome Clinical Trial
Updated: 12/31/1969
Steroids for Pediatric Apnea Research in Kids
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Duchenne Muscular Dystrophy Clinical Trial
Updated: 12/31/1969
Study of SRP-4045 and SRP-4053 in DMD Patients
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 12/31/1969
Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia
Status: Enrolling
Updated: 12/31/1969
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Otolaryngology, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit?
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hospitalized Neonates and Infants, Expected to Require Parenteral Nutrition for 28 Days Clinical Trial
Updated: 12/31/1969
Phase 3 Study to Compare Safety and Efficacy of Smoflipid 20% to Intralipid 20% in Hospitalized Neonates and Infants
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Seizures Clinical Trial
Updated: 4/15/2016
Cannabidiol Oral Solution in Pediatric Subjects With Treatment- Resistant Seizure Disorders
Status: Enrolling,
Phase
I, II
Updated: 4/15/2016
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Hodgkin Lymphoma Clinical Trial
Updated: 12/31/1969
Pilot Study of Non-Viral, RNA-Redirected Autologous T Cells in Patients With Refractory or Relapsed Hodgkin Lymphoma
Status: Enrolling,
Phase
Updated: 12/31/1969
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Acute Lymphoblastic Leukemia Clinical Trial
Updated: 12/31/1969
Study Evaluating KTE-C19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Adolescent Idiopathic Scoliosis Clinical Trial
Updated: 4/10/2018
Adolescent Idiopathic Scoliosis Outcomes Database Registry
Status: Enrolling,
Phase
Updated: 4/10/2018
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Neurology, Other Clinical Trial
Updated: 4/3/2018
Natural History of Rett Syndrome & Related Disorders
Status: Enrolling,
Phase
Updated: 4/3/2018
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Other Clinical Trial
Updated: 12/31/1969
A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hyperphosphatemia Clinical Trial
Updated: 12/31/1969
An Study to Investigate the Safety and Efficacy of PA21 (Velphoro®) and Calcium Acetate (Phoslyra®) in Paediatric and Adolescent Chronic Kidney Disease (CKD) Patients With Hyperphosphataemia
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Endocrinology, Neurology Clinical Trial
Updated: 12/31/1969
Intranasal Oxytocin in Hypothalamic Obesity
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Tuberous Sclerosis Complex Clinical Trial
Updated: 12/31/1969
Preventing Epilepsy Using Vigabatrin In Infants With Tuberous Sclerosis Complex
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Type 2 Diabetes Clinical Trial
Updated: 12/31/1969
A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Leukemia Clinical Trial
Updated: 12/31/1969
A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Next Generation Personalized Neuroblastoma Therapy
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hepatitis C Virus Infection Clinical Trial
Updated: 12/31/1969
Sofosbuvir/Velpatasvir in Adolescents and Children With Chronic HCV Infection
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Chronic Pancreatitis Clinical Trial
Updated: 2/2/2018
Fat Malabsorption in Chronic Pancreatitis
Status: Enrolling,
Phase
II
Updated: 2/2/2018
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
Updated: 5/1/2018
PEEP and V/Q Mismatch in Premature Infants
Status: Enrolling,
Phase
I, II
Updated: 5/1/2018
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Gastroenterology Clinical Trial
Updated: 12/31/1969
Vedolizumab IV in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hemophilia A Clinical Trial
Updated: 12/31/1969
A Gene Transfer Study for Hemophilia A
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Oncology, Other Clinical Trial
Updated: 12/31/1969
Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Severe Aplastic Anemia Clinical Trial
Updated: 12/31/1969
Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia
Status: Enrolling
Updated: 12/31/1969
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Peanut Allergy Clinical Trial
Updated: 12/31/1969
Long-term Safety Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Psychiatry / Psychology Clinical Trial
Updated: 12/31/1969
Addressing Traumatic Stress Symptoms in Children
Status: Enrolling
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Pharmacology / Toxicology Clinical Trial
Updated: 12/31/1969
Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-913 in Subjects With MPS II
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
Updated: 5/1/2018
Impact of CPAP Level on V/Q Mismatch in Premature Infants
Status: Enrolling
Updated: 5/1/2018
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Idiopathic Scoliosis Clinical Trial
Updated: 12/31/1969
Vertebral Body Tethering Outcomes for Pediatric Idiopathic Scoliosis
Status: Enrolling
Updated: 12/31/1969
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Childhood Absence Epilepsy Clinical Trial
Updated: 12/31/1969
Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Spinal Muscular Atrophy Clinical Trial
Updated: 12/31/1969
Study of Intrathecal Administration of AVXS-101 for Spinal Muscular Atrophy
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Psychiatry / Psychology Clinical Trial
Updated: 12/31/1969
Impact of Beds for Kids Program on Child Sleep
Status: Enrolling
Updated: 12/31/1969
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Single Ventricle Heart Disease Clinical Trial
Updated: 12/31/1969
Evaluation of Fontan-Associated Liver Disease
Status: Enrolling,
Phase
Updated: 12/31/1969
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Clinical Trial
Updated: 12/31/1969
Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Endocrinology Clinical Trial
Updated: 4/19/2018
Integrating Community Health Workers Into the Care of Children With Type 1 Diabetes
Status: Enrolling
Updated: 4/19/2018
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Other Clinical Trial
Updated: 12/31/1969
Effectiveness of Contrast-Enhanced Ultrasound
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Precursor Cell Lymphoblastic Leukemia-Lymphoma Clinical Trial
Updated: 12/31/1969
A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Clinical Trial
Updated: 12/31/1969
A Study of MACI in Patients Aged 10 to
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Expanded Access Protocol Using Alpha/Beta T and CD19+ Depleted PBSC
Status: Enrolling,
Phase
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Hematology Clinical Trial
Updated: 12/31/1969
Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Hematology Clinical Trial
Updated: 12/31/1969
Shared-Decision Making for Hydroxyurea
Status: Enrolling
Updated: 12/31/1969
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 12/31/1969
Flourish™ Pediatric Esophageal Atresia
Status: Enrolling,
Phase
Updated: 12/31/1969
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Dermatology / Plastic Surgery Clinical Trial
Updated: 12/31/1969
Evaluation of the Safety and Efficacy Study of RGN-137 Topical Gel for Junctional and Dystrophic Epidermolysis Bullosa
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hypoplastic Left Heart Syndrome Clinical Trial
Updated: 12/31/1969
Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome (AutoCell-S2)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Hyperinsulinism-Hyperammonemia Syndrome Clinical Trial
Updated: 12/31/1969
Vitamin E Supplementation in Hyperinsulinism/Hyperammonemia Syndrome
Status: Enrolling
Updated: 12/31/1969
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Childhood Sleep Promotion Clinical Trial
Updated: 12/31/1969
Increasing Childhood Sleep Duration in the Primary Care Setting
Status: Enrolling
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 12/31/1969
A Prospective Database of Infants With Cholestasis
Status: Enrolling,
Phase
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 2/15/2018
Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC)
Status: Enrolling
Updated: 2/15/2018
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
Nasal Potential Difference (NPD) for the Diagnosis of Cystic Fibrosis
Status: Enrolling
Updated: 12/31/1969
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Endocrinology, Other Clinical Trial
Updated: 2/24/2015
Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 1
Status: Enrolling,
Phase
II
Updated: 2/24/2015
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Neurology, Orthopedics / Podiatry Clinical Trial
Updated: 4/10/2018
Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
Status: Enrolling,
Phase
Updated: 4/10/2018
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Hematology, Immunology / Infectious Diseases, Oncology, Other Clinical Trial
Updated: 12/31/1969
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Status: Enrolling,
Phase
Updated: 12/31/1969
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Brain and Central Nervous System Tumors Clinical Trial
Updated: 6/22/2011
ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors
Status: Enrolling
Updated: 6/22/2011
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Charcot Marie Tooth Disease Clinical Trial
Updated: 12/31/1969
Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
Status: Enrolling,
Phase
Updated: 12/31/1969
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Hematology, Neurology Clinical Trial
Updated: 12/31/1969
Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Brain and Central Nervous System Tumors Clinical Trial
Updated: 1/7/2011
Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy
Status: Enrolling
Updated: 1/7/2011
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Duchenne Muscular Dystrophy Clinical Trial
Updated: 12/31/1969
Study of Ataluren in Previously Treated Participants With Nonsense Mutation Dystrophinopathy (nmDBMD)
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Hypoplastic Left Heart Syndrome Clinical Trial
Updated: 12/31/1969
Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Critical Injury (Trauma) in Children Clinical Trial
Updated: 12/31/1969
GM-CSF for Immunomodulation Following Trauma (GIFT) Study
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Congenital Sucrase-isomaltase Deficiency CSID Clinical Trial
Updated: 6/10/2014
Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS)
Status: Enrolling
Updated: 6/10/2014
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Pharmacokinetics in Obese Adolescents Clinical Trial
Updated: 12/23/2013
Single Dose Study to Determine the Safety, Tolerability, and Pharmacokinetic Properties of Lorcaserin Hydrochloride (BELVIQ) in Obese Adolescents From 12 to 17 Years of Age
Status: Enrolling,
Phase
I
Updated: 12/23/2013
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Oncology Clinical Trial
Updated: 12/31/1969
Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Bone Mineral Density Reference Data Clinical Trial
Updated: 12/31/1969
Bone Mineral Accretion in Young Children
Status: Enrolling,
Phase
Updated: 12/31/1969
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