Children's Hospital of Philadelphia
Since its start in 1855 as the nation's first hospital devoted exclusively to caring for children, The Children's Hospital of Philadelphia has been the birthplace for many dramatic firsts in pediatric medicine. The Hospital has fostered medical discoveries and innovations that have improved pediatric healthcare and saved countless children’s lives. Over 150 years of innovation and service to our patients, their families and our community, reflect an ongoing commitment to exceptional patient care.
We've found
402 trials
at this facility
Clinical Trial
Updated: 3/16/2018
The Myelin Disorders Biorepository Project
Status: Enrolling,
Phase
Updated: 3/16/2018
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Neoplasm Clinical Trial
Updated: 12/31/1969
Crizotinib (Xalkori) Expanded Access Protocol For The Treatment Of Adult Or Pediatric Patients
Status: Enrolling,
Phase
Updated: 12/31/1969
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Atrial Septal Defect Clinical Trial
Updated: 12/31/1969
Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs
Status: Enrolling
Updated: 12/31/1969
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HIV Clinical Trial
Updated: 12/31/1969
Youth mHealth Adherence Intervention for HIV+ YMSM
Status: Enrolling
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
Status: Enrolling,
Phase
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
HeadStart4: Newly Diagnosed Children (
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Diabetes Mellitus, Type 2 Clinical Trial
Updated: 12/31/1969
A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Pulmonary / Respiratory Diseases, Other Clinical Trial
Updated: 12/31/1969
Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Creatine Deficiency, X-linked Clinical Trial
Updated: 12/31/1969
Observational Study of Males With Creatine Transporter Deficiency
Status: Enrolling,
Phase
Updated: 12/31/1969
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Other Clinical Trial
Updated: 12/31/1969
Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Cardiology / Vascular Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study
Status: Enrolling
Updated: 12/31/1969
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Neuroblastoma Clinical Trial
Updated: 12/31/1969
Study of Lorlatinib (PF-06463922)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Bronchopulmonary Dysplasia Clinical Trial
Updated: 12/31/1969
Fluid Filled Lung Oxygenation Assistance Trial
Status: Enrolling,
Phase
Updated: 12/31/1969
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Adenovirus Clinical Trial
Updated: 12/31/1969
The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Von Willebrand Disease Clinical Trial
Updated: 2/15/2018
BAX 111 rVWF in Pediatrics
Status: Enrolling,
Phase
III
Updated: 2/15/2018
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Recurrent and Refractory Solid Tumors Clinical Trial
Updated: 12/31/1969
Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Diabetes Mellitus, Type 1 Clinical Trial
Updated: 12/31/1969
MyDiaText Text Messaging Intervention for Diabetes
Status: Enrolling
Updated: 12/31/1969
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
A Study to Evaluate the Safety of Long-term Ivacaftor Treatment in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age at Treatment Initiation and Have an Approved Ivacaftor-Responsive Mutation
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Childhood Sleep Promotion Clinical Trial
Updated: 12/31/1969
Mobile Health Sleep and Growth Study 2
Status: Enrolling
Updated: 12/31/1969
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Homocystinuria Clinical Trial
Updated: 12/31/1969
OT-58 as an Enzyme Replacement Therapy for Patients With Cystathionine Beta-Synthase Deficient Homocystinuria (CBSDH)
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Medication Adherence Clinical Trial
Updated: 12/31/1969
Motivational Enhancement System for Adherence (MESA) for Youth Starting ART
Status: Enrolling
Updated: 12/31/1969
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Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
Updated: 12/31/1969
BPD Saturation TARgeting
Status: Enrolling
Updated: 12/31/1969
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Cardiology / Vascular Diseases, Neurology Clinical Trial
Updated: 12/31/1969
CEUS Evaluation of Hypoxic Ischemic Injury
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Autism Spectrum Disorder Clinical Trial
Updated: 12/31/1969
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Axitinib and Nivolumab in Treating Participants With Unresectable or Metastatic TFE/Translocation Renal Cell Carcinoma
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Duchenne Muscular Dystrophy Clinical Trial
Updated: 12/31/1969
Expanded Access Program for Idebenone in Participants With Duchenne Muscular Dystrophy (DMD)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Oncology, Other Clinical Trial
Updated: 12/31/1969
Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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HIV INfections Clinical Trial
Updated: 12/31/1969
Young Men's Health Project Targeting HIV Risk Reduction and Substance Abuse
Status: Enrolling
Updated: 12/31/1969
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Type1 Diabetes Mellitus Clinical Trial
Updated: 12/31/1969
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Subjects 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Inflammatory Bowel Diseases Clinical Trial
Updated: 12/31/1969
Treating IBD With Inulin
Status: Enrolling
Updated: 12/31/1969
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Hypoparathyroidism Clinical Trial
Updated: 12/31/1969
Study of the Effect of Recombinant Human Parathyroid Hormone [rhPTH(1-84)] on Symptoms Improvement and Metabolic Control Among Adults With Hypoparathyroidism
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Septic Shock Clinical Trial
Updated: 12/31/1969
Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis
Status: Enrolling,
Phase
Updated: 12/31/1969
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Cystic Fibrosis Clinical Trial
Updated: 12/31/1969
Orkambi Treatment in 2 to 5 Year Old Children With CF
Status: Enrolling,
Phase
Updated: 12/31/1969
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Psychiatry / Psychology Clinical Trial
Updated: 12/31/1969
Melatonin Effects on Sleep and Circadian Rhythm in Youth and Young Adults With At-risk Symptoms
Status: Enrolling
Updated: 12/31/1969
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Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Status: Enrolling,
Phase
Updated: 12/31/1969
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Neurology, Other Clinical Trial
Updated: 12/31/1969
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 12/31/1969
Predicting Response to Vedolizumab in Pediatric Inflammatory Bowel Diseases
Status: Enrolling
Updated: 12/31/1969
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Lupus Erythematosus, Systemic Clinical Trial
Updated: 6/23/2005
Role of Altered CD40-Ligand Gene Transcription in Systemic Lupus Erythematosus
Status: Enrolling
Updated: 6/23/2005
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Neuroblastoma Clinical Trial
Updated: 4/5/2011
Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
Status: Enrolling
Updated: 4/5/2011
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Mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy Syndrome) Clinical Trial
Updated: 12/31/1969
Mucopolysaccharidosis (MPS) VI Clinical Surveillance Program (CSP)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Hematology, Oncology, Orthopedics / Podiatry Clinical Trial
Updated: 8/3/2012
Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission
Status: Enrolling
Updated: 8/3/2012
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Neurology, Oncology, Psychiatry / Psychology, Other Clinical Trial
Updated: 12/31/1969
Neuropsychological and Behavioral Testing in Younger Patients With Cancer
Status: Enrolling,
Phase
Updated: 12/31/1969
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Hematology Clinical Trial
Updated: 5/31/2016
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome
Status: Enrolling,
Phase
I
Updated: 5/31/2016
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Oncology Clinical Trial
Updated: 10/7/2013
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Status: Enrolling,
Phase
II
Updated: 10/7/2013
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Antiretroviral Toxicity Clinical Trial
Updated: 12/31/1969
Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women
Status: Enrolling,
Phase
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 5/2/2018
Compassionate Use of Omegaven for Pediatric Patients With Parenteral Nutrition Associated Liver Disease
Status: Enrolling,
Phase
Updated: 5/2/2018
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Chronic Kidney Disease Clinical Trial
Updated: 12/31/1969
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Immunology / Infectious Diseases, Ophthalmology, Reproductive Clinical Trial
Updated: 12/31/1969
Patients Treated for SCID (1968-Present)
Status: Enrolling,
Phase
Updated: 12/31/1969
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Hematology, Oncology Clinical Trial
Updated: 7/12/2012
MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia
Status: Enrolling
Updated: 7/12/2012
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Immunology / Infectious Diseases Clinical Trial
Updated: 12/31/1969
TMC125-TiDP35-C239 - Continued Access to Etravirine (ETR) in Treatment Experienced HIV-1 Infected Children and Adolescents
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Gastroenterology Clinical Trial
Updated: 12/31/1969
Longitudinal Study of Mitochondrial Hepatopathies
Status: Enrolling,
Phase
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Neuroblastoma Clinical Trial
Updated: 12/31/1969
131I-MIBG Alone VS. 131I-MIBG With Vincristine and Irinotecan VS131I-MIBG With Vorinistat
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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B Acute Lymphoblastic Leukemia Clinical Trial
Updated: 12/31/1969
Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Spinal Muscular Atrophy Clinical Trial
Updated: 3/16/2016
A Study to Assess the Efficacy and Safety of IONIS-SMN Rx in Infants With Spinal Muscular Atrophy
Status: Enrolling,
Phase
III
Updated: 3/16/2016
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Oncology Clinical Trial
Updated: 12/31/1969
Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Epilepsy Clinical Trial
Updated: 12/31/1969
A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Venous Thromboembolism Clinical Trial
Updated: 12/31/1969
Apixaban for the Acute Treatment of Venous Thromboembolism in Children
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Cardiology / Vascular Diseases Clinical Trial
Updated: 12/31/1969
Syncardia 50cc TAH-t as a Bridge to Transplant
Status: Enrolling
Updated: 12/31/1969
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Invasive Candidiasis Clinical Trial
Updated: 12/31/1969
BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia
Status: Enrolling,
Phase
Updated: 12/31/1969
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Endocrinology, Gastroenterology, Hematology, Immunology / Infectious Diseases, Oncology, Other Clinical Trial
Updated: 12/31/1969
Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC
Status: Enrolling,
Phase
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Expanded Access Protocol for Tabelecleucel in Subjects With EBV-Associated Viremia or Malignancies
Status: Enrolling,
Phase
Updated: 12/31/1969
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Ulcerative Colitis (UC) Clinical Trial
Updated: 12/31/1969
Use of a Novel Diet (UC DIET) for Treatment of Mild to Moderate Active Pediatric Ulcerative Colitis
Status: Enrolling,
Phase
IV
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
CD22 Redirected Autologous T Cells for ALL
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Matched Targeted Therapy For High-Risk Leukemias and MDS
Status: Enrolling
Updated: 12/31/1969
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Thrombosis Clinical Trial
Updated: 12/31/1969
Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Prexasertib in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hematology Clinical Trial
Updated: 12/31/1969
Rituximab and LMP-Specific T-Cells in Treating Pediatric Solid Organ Recipients With EBV-Positive, CD20-Positive Post-Transplant Lymphoproliferative Disorder
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Developmental Dysplasia of the Hip Clinical Trial
Updated: 12/31/1969
Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow After Surgical Hip Reduction for DDH
Status: Enrolling,
Phase
Updated: 12/31/1969
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Duchenne Muscular Dystrophy Clinical Trial
Updated: 12/31/1969
Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Duchenne Muscular Dystrophy
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Immunology / Infectious Diseases, Oncology Clinical Trial
Updated: 12/31/1969
Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Polycystic Kidney, Autosomal Recessive Clinical Trial
Updated: 12/31/1969
A Safety, Pharmacokinetic, Single Ascending Dose Study of Tesevatinib in Pediatric Subjects With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hematological Malignancy Clinical Trial
Updated: 12/31/1969
A Study of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Hypoplastic Left Heart Syndrome Clinical Trial
Updated: 12/31/1969
Cerebral Anatomy, Hemodynamics and Metabolism
Status: Enrolling,
Phase
Updated: 12/31/1969
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Other, Reproductive Clinical Trial
Updated: 12/31/1969
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Suspected or Documented Gram-negative Bacterial Infection Clinical Trial
Updated: 12/31/1969
A Pharmacokinetics Study of MK-7655A in Pediatric Participants With Gram-negative Infections (MK-7655A-020)
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Oncology Clinical Trial
Updated: 12/31/1969
Pevonedistat, Irinotecan Hydrochloride, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Status: Enrolling,
Phase
I
Updated: 12/31/1969
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Headache Disorders Clinical Trial
Updated: 11/2/2017
Oral Microbiome and Inflammation in Pediatric Headache
Status: Enrolling
Updated: 11/2/2017
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Urinary Stones Clinical Trial
Updated: 12/31/1969
Prevention of Urinary Stones With Hydration
Status: Enrolling
Updated: 12/31/1969
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Veno-occlusive Disease Clinical Trial
Updated: 12/31/1969
Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Obstructive Sleep Apnea Syndrome Clinical Trial
Updated: 12/31/1969
CBF and Childhood OSAS
Status: Enrolling,
Phase
Updated: 12/31/1969
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Immunology / Infectious Diseases Clinical Trial
Updated: 12/31/1969
High Dose Flu Vaccine in Treating Children Who Have Undergone Donor Stem Cell Transplant
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Mixed Tumor, Malignant Clinical Trial
Updated: 12/31/1969
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Status: Enrolling,
Phase
I, II
Updated: 12/31/1969
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Ulcerative Colitis Clinical Trial
Updated: 12/31/1969
Microbiota-targeted Diet for Pediatric UC
Status: Enrolling
Updated: 12/31/1969
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Orthopedics / Podiatry Clinical Trial
Updated: 12/31/1969
Postoperative and Chronic Pain Genetic Spine Surgery Study
Status: Enrolling,
Phase
Updated: 12/31/1969
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Friedreich Ataxia Clinical Trial
Updated: 12/31/1969
Neurology Measures in FA Children
Status: Enrolling,
Phase
Updated: 12/31/1969
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Cardiology / Vascular Diseases, Hematology, Immunology / Infectious Diseases, Nephrology / Urology Clinical Trial
Updated: 12/31/1969
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
West Philadelphia Controls Asthma
Status: Enrolling
Updated: 12/31/1969
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Pulmonary / Respiratory Diseases Clinical Trial
Updated: 12/31/1969
PPIs and Fat Absorption in CF and EPI
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Rett Syndrome Clinical Trial
Updated: 12/31/1969
A Study to Evaluate Ketamine for the Treatment of Rett Syndrome
Status: Enrolling,
Phase
II
Updated: 12/31/1969
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Muscular Dystrophy, Duchenne Clinical Trial
Updated: 12/31/1969
Phase III Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy
Status: Enrolling,
Phase
III
Updated: 12/31/1969
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Palliative Care Clinical Trial
Updated: 12/31/1969
Acupuncture Intervention for AYA With Cancer
Status: Enrolling
Updated: 12/31/1969
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