Cincinnati Children's Hospital Medical Center
3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
 1-513-636-4200  http://www.cincinnatichildrens.org/default/

Use our guide to learn which trials are right for you!

Patients and families from across the region and around the world come to Cincinnati Children’s Hospital Medical Center because we are dedicated to improving child health.

Other medical providers often turn to us when a child needs a complex surgical procedure or treatment for a rare pediatric disease. We discover new and better ways to treat the conditions that affect children, maintaining our status as one of the world’s foremost centers for pediatric care.

U.S. News & World Report ranked Cincinnati Children’s as one of the nation’s top three pediatric hospitals, but we’re far more than a number or ranking. We are a resource for your family. We are also a positive force in the community, improving public health for children. And we’re a partner with patients and families in pursuit of the best possible healthcare outcomes for every child we treat.

We've found
357 trials
at this facility
Hematopoietic Stem Cell Transplantation Clinical Trial
A Pharmacokinetic Study of Melphalan in Children
Status: Enrolling, Phase I
Updated: 12/31/1969
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Cincinnati, OH
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Project: Every Child for Younger Patients With Cancer
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Acute Lymphoblastic Leukemia (ALL) Clinical Trial
Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Major Depressive Disorder Clinical Trial
Safety and Efficacy of Levomilnacipran ER in Adolescent Patients With Major Depressive Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Respiratory Disorders Clinical Trial
Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Pulmonary Alveolar Proteinosis Clinical Trial
A National Registry For Pulmonary Alveolar Proteinosis
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Endocrinology, Hematology, Oncology Clinical Trial
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Hematology, Oncology, Other Clinical Trial
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology, Other Clinical Trial
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (PNs)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Malignant Hyperthermia Clinical Trial
A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Cincinnati, OH
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Cystic Fibrosis Clinical Trial
Exploratory Study to Evaluate QR-010 in Subjects With Cystic Fibrosis ΔF508 CFTR Mutation
Status: Enrolling, Phase I
Updated: 6/21/2016
mi
from
Cincinnati, OH
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Oncology Clinical Trial
A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Acute Lung Injury Clinical Trial
L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Hodgkin Disease Clinical Trial
A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Diabetes Mellitus, Type 2 Clinical Trial
Phase 3 Alogliptin Pediatric Study
Status: Enrolling, Phase III
Updated: 12/31/1969
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Cincinnati, OH
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Thrombosis Clinical Trial
A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Lymphoma, Non-Hodgkin Clinical Trial
A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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BIPOLAR DISORDER Clinical Trial
Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs
Status: Enrolling, Phase IV
Updated: 6/1/2016
mi
from
Cincinnati, OH
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Cystic Fibrosis Clinical Trial
Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Hypoplastic Left Heart Syndrome (HLHS) Clinical Trial
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
Status: Enrolling, Phase
Updated: 4/9/2018
mi
from
Cincinnati, OH
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Cincinnati, OH
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Pulmonary / Respiratory Diseases Clinical Trial
A Study of AeroVanc for the Treatment of MRSA Infection in CF Patients
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Allogeneic Hematopoietic Cell Transplantation Clinical Trial
Precision Dosing of Alemtuzumab
Status: Enrolling
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Malignant Hyperthermia Clinical Trial
Malignant Hyperthermia Registry and Genetic Testing
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Eosinophilic Esophagitis Clinical Trial
CEGIR 7807: Validation of Online Cohort of EGID Patients Enrolled in RDCRN CEGIR Contact Registry
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Cincinnati, OH
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Von Willebrand Disease Clinical Trial
BAX 111 rVWF in Pediatrics
Status: Enrolling, Phase III
Updated: 2/15/2018
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from
Cincinnati, OH
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Adenovirus Clinical Trial
The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation
Status: Enrolling, Phase II
Updated: 12/31/1969
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from
Cincinnati, OH
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Recurrent and Refractory Solid Tumors Clinical Trial
Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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HLHS Clinical Trial
Longeveron Mesenchymal Stem Cells (LMSCs) Delivered During Stage II Surgery for Hypoplastic Left Heart Syndrome (ELPIS)
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Pulmonary / Respiratory Diseases Clinical Trial
A Study to Evaluate the Safety, Tolerability and Immunogenicity of an Investigational RSV Vaccine Candidate (Ad26.RSV.preF) in Adults 18 to 50 Years of Age, and RSV-seropositive Toddlers 12 to 24 Months of Age
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Fabry Disease Clinical Trial
Extension Study of 1 mg/kg Pegunigalsidase Alfa in Patients With Fabry Disease
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Veliparib, Radiation Therapy, and Temozolomide in Treating Participants With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600E Mutations
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Axitinib and Nivolumab in Treating Participants With Unresectable or Metastatic TFE/Translocation Renal Cell Carcinoma
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Gastroenterology, Immunology / Infectious Diseases Clinical Trial
MRI Based Biomarkers in Pediatric Autoimmune Liver Disease
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Vigil + Irinotecan and Temozolomide in Ewing's Sarcoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases Clinical Trial
Safety of LAIV4 in Children With Asthma
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Niemann-Pick Type C Disease Clinical Trial
An Open-label Treatment Protocol for VTS-270 in Patients With Neurologic Manifestations of NPC
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Oncology Clinical Trial
Pembrolizumab in Combination With Decitabine and Hypofractionated Index Lesion Radiation in Pediatrics and Young Adults
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Cincinnati, OH
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Nephrology / Urology, Neurology Clinical Trial
VIRTUUS Children's Study
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Cincinnati, OH
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Chronic Graft Versus Host Disease Clinical Trial
Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)
Status: Enrolling, Phase I, II
Updated: 12/31/1969
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from
Cincinnati, OH
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Crohn Disease Clinical Trial
Early MRI Prediction of Crohns
Status: Enrolling, Phase
Updated: 12/31/1969
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Cincinnati, OH
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Complex Regional Pain Syndromes Clinical Trial
Markers of Trajectory in Pediatric CRPS
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Cincinnati, OH
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Neurology, Psychiatry / Psychology, Orthopedics / Podiatry Clinical Trial
Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Gastroenterology Clinical Trial
Intestinal Microbiome Composition in Infants With Biliary Atresia (BA)
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Brain Injury Traumatic Mild Clinical Trial
Web-Based Self-Monitoring Activity-Restriction and Relaxation Training Program for Kids With Mild Traumatic Brain Injury
Status: Upcoming
Updated: 4/12/2018
mi
from
Cincinnati, OH
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Bronchiolitis Obliterans Clinical Trial
Hp129 Xenon Imaging and BOS in Lung Transplantation
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Gastroenterology Clinical Trial
DEGS - Dupilumab for Eosinophilic Gastritis Study
Status: Upcoming, Phase II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Type 1 Diabetes Mellitus Clinical Trial
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Psychiatry / Psychology, Other Clinical Trial
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Status: Upcoming, Phase IV
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Smith-Lemli-Opitz Syndrome Clinical Trial
Smith-Lemli-Opitz Syndrome and Cholic Acid
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Pyruvate Kinase Deficiency Clinical Trial
Extension Study of AG-348 in Adult Participants With Pyruvate Kinase Deficiency Previously Enrolled in AG-348-006 or AG348-C-007
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Cincinnati, OH
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Eosinophilic Gastritis or Gastroenteritis Clinical Trial
Benralizumab for Eosinophilic Gastritis
Status: Upcoming, Phase I, II
Updated: 3/21/2018
mi
from
Cincinnati, OH
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Gastroenterology Clinical Trial
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Cincinnati, OH
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