Clinical Trials in North Carolina

Are you looking to enroll in a clinical trial in North Carolina? With new trials like "Effectiveness and Safety of CELSTAT for Hemostasis in Intraoperative Tissue Bleeding" and "Liver Test Study of Using JKB-122 in AIH Patients", the Old North State has established itself as a great location for clinical research studies, particularly in cities like Durham and Raleigh.

While some individuals are looking for paid clinical trials, others want to help advance hematology and toxicology clinical research in North Carolina. To begin your search for North Carolina clinical trials, use the form on the right.

Use our guide to learn which trials are right for you!


We've found
6,260
clinical trials in
North Carolina

Chronic Lymphocytic Leukemia Clinical Trial
Ibrutinib and Obinutuzumab With or Without Venetoclax in Treating Older Patients With Untreated Chronic Lymphocytic Leukemia
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Chronic Lymphocytic Leukemia Clinical Trial
Ibrutinib and Obinutuzumab With or Without Venetoclax in Treating Older Patients With Untreated Chronic Lymphocytic Leukemia
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Fragile X Syndrome Clinical Trial
Open Label Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Oncology Clinical Trial
Ibrutinib and Obinutuzumab With or Without Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Goldsboro, NC
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Oncology Clinical Trial
Ibrutinib and Obinutuzumab With or Without Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Jacksonville, NC
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Gastroenterology Clinical Trial
Genetic-specific Effects of Fructose on Liver Lipogenesis
Status: Enrolling
Updated: 12/31/1969
mi
from
Kannapolis, NC
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Urinary Bladder, Overactive Clinical Trial
FemPulse Therapy for Overactive Bladder in Women
Status: Enrolling
Updated: 12/31/1969
mi
from
Charlotte, NC
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Breast Cancer Clinical Trial
ARFI, VisR and DDAI Ultrasound for Improving Discrimination of Malignant and Unresponsive Breast Cancer
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Head and Neck Neoplasms Clinical Trial
Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Charlotte, NC
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Pancreatic Cancer Metastatic Clinical Trial
Study Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the Pancreas
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Infertility Clinical Trial
Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-1)
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Raleigh, NC
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Colo-rectal Cancer Clinical Trial
Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Charlotte, NC
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Musculoskeletal Clinical Trial
Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Durham, NC
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Systemic Lupus Erythematosus (SLE) Clinical Trial
Omega-3 Replacement With Krill Oil in Disease Management of SLE
Status: Enrolling
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Oncology, Other Clinical Trial
Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Gastroenterology, Immunology / Infectious Diseases Clinical Trial
A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Fayetteville, NC
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Ventricular Tachycardia Clinical Trial
FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study
Status: Enrolling
Updated: 12/31/1969
mi
from
Raleigh, NC
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Anhedonia Clinical Trial
Development of a Novel Transdiagnostic Intervention for Anhedonia
Status: Enrolling
Updated: 12/31/1969
mi
from
CHapel Hill, NC
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Cardiology / Vascular Diseases, Endocrinology, Hematology, Nephrology / Urology, Pulmonary / Respiratory Diseases, Reproductive Clinical Trial
Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Oncology Clinical Trial
A Registry to Evaluate the Performance of the BDX-XL2 Test
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Pinehurst, NC
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Oncology Clinical Trial
A Registry to Evaluate the Performance of the BDX-XL2 Test
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Lung Transplantation Clinical Trial
OCS™ Lung TOP Registry
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Psoriasis Clinical Trial
Apremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical Safety and Efficacy
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Musculoskeletal Clinical Trial
Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Hematologic Malignancy Clinical Trial
A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Melanoma Clinical Trial
Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Respiratory Syncytial Virus Infections Clinical Trial
A Study to Assess the Safety, Reactogenicity and Immune Response of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3844766A) in Older Adults
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Hickory, NC
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Weight Gain Clinical Trial
Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis
Status: Enrolling
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Emotions Clinical Trial
Emotion Regulation and Emotion Perception
Status: Enrolling
Updated: 12/31/1969
mi
from
Durham, NC
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Pulmonary / Respiratory Diseases, Other Clinical Trial
CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients
Status: Enrolling
Updated: 12/31/1969
mi
from
Durham, NC
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Oncology Clinical Trial
Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Burlington, NC
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Oncology Clinical Trial
Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Wilkesboro, NC
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Oncology Clinical Trial
Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Oncology Clinical Trial
Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Previously Treated Non-Small Cell Lung Cancer Clinical Trial
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Mebane, NC
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Previously Treated Non-Small Cell Lung Cancer Clinical Trial
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Pinehurst, NC
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Neurology, Psychiatry / Psychology Clinical Trial
A Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Charlotte, NC
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Duchenne Muscular Dystrophy Clinical Trial
Expanded Access Protocol for Boys With Duchenne Muscular Dystrophy
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Endocrinology Clinical Trial
Healthy Mothers-Healthy Children Nutrition and Physical Activity Intervention
Status: Enrolling
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Oncology Clinical Trial
A Study to Evaluate Concurrent VRP-HER2 Vaccination and Pembrolizumab for Patients With Breast Cancer
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Durham, NC
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Hematology, Nephrology / Urology Clinical Trial
Study of Vadadustat in Hemodialysis Patients With Anemia Switching From Epoetin Alfa
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Asheville, NC
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
Clinical Utility for Ion Endoluminal System
Status: Enrolling
Updated: 12/31/1969
mi
from
Pinehurst, NC
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Depressive Disorder, Treatment-Resistant Clinical Trial
A Long-term Safety Study of Intranasal Esketamine in Treatment-resistant Depression
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Durham, NC
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Neurology, Otolaryngology, Pulmonary / Respiratory Diseases, Other Clinical Trial
Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract
Status: Upcoming, Phase I
Updated: 2/9/2016
mi
from
Chapel Hill, NC
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Hypertension Clinical Trial
Aliskiren Study of Safety and Efficacy in Senior Hypertensives
Status: Upcoming, Phase IV
Updated: 1/5/2015
mi
from
Shelby, NC
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Normal Eyelid Sensation Distribution Clinical Trial
Normal Eyelid Sensation Distribution
Status: Upcoming
Updated: 2/7/2014
mi
from
Durham, NC
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Hematology Clinical Trial
Continuous Hemoglobin Monitoring: Detection of Acute Blood Loss - Accurate, Timely and Cost-effective
Status: Upcoming
Updated: 5/12/2014
mi
from
Charlotte, NC
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Dehydration Clinical Trial
Hydration Monitor Validation in Elderly
Status: Upcoming
Updated: 7/30/2014
mi
from
Boone, NC
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Biological Specimens Clinical Trial
Rapid Acquisition of Pre- and Post-Incident Disaster Data
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Research Triangle Park, NC
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Preterm Delivery Clinical Trial
Trial Exploring the Efficacy and Safety of FE 202767
Status: Upcoming, Phase II
Updated: 5/9/2016
mi
from
Raleigh, NC
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Nephrology / Urology Clinical Trial
Acthar for Treatment of Post-transplant FSGS
Status: Upcoming, Phase IV
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Inflammatory Disease Clinical Trial
Inhaled Nanosilver Study
Status: Upcoming
Updated: 10/18/2017
mi
from
Research Triangle Park, NC
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Other Clinical Trial
Hearing Loss in Older Adults Study
Status: Upcoming
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Posttraumatic Stress Disorder Clinical Trial
Neurosteroids in PTSD - Biomarkers to Therapeutics
Status: Upcoming, Phase II
Updated: 12/31/1969
mi
from
Durham, NC
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Oncology, Pulmonary / Respiratory Diseases Clinical Trial
A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Endocrinology Clinical Trial
Exercise After Clinically Significant Weight Loss
Status: Upcoming
Updated: 12/31/1969
mi
from
Greenville, NC
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Ankle Sprains Clinical Trial
Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation
Status: Upcoming
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Musculoskeletal Clinical Trial
Treating Pain With Acceptance and Commitment Therapy Trial
Status: Upcoming
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Polytrauma Clinical Trial
Inflammatory Markers in Trauma Patient Outcomes
Status: Upcoming, Phase I
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Nephrology / Urology Clinical Trial
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Psychiatry / Psychology Clinical Trial
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Status: Upcoming, Phase IV
Updated: 12/31/1969
mi
from
Salisbury, NC
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Neurology, Psychiatry / Psychology Clinical Trial
Neurotechnology Following Traumatic Brain Injury
Status: Upcoming
Updated: 12/31/1969
mi
from
Fort Bragg, NC
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Opioid Use Clinical Trial
Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films
Status: Upcoming, Phase II
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Oncology Clinical Trial
Accuracy for Predicting Deep Submucosal Invasion
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Neurology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Sleep for Stroke Management and Recovery Trial
Status: Upcoming
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Invasive Bladder Cancer Clinical Trial
Testing the Utilization of a Mobile Health App for Patients Undergoing Cystectomy Surgery for Bladder Cancer
Status: Upcoming
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Orthopedics / Podiatry Clinical Trial
Safety and Performance of PEEK Anchors (Dynomite, Spyromite, Raptomite) in Extremities
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Charlotte, NC
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Thoracoabdominal Aortic Aneurysm Clinical Trial
Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
Status: Upcoming
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Endocrinology Clinical Trial
Metabolics of Roux-en-Y Gastric Bypass (RYGB) With Gastrostomy
Status: Upcoming
Updated: 4/22/2009
mi
from
Greenville, NC
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Autism Clinical Trial
Collaborative Study Of Neurofeedback Training Of 6-18 Year Olds With Autism
Status: Upcoming, Phase I
Updated: 10/3/2010
mi
from
Raleigh, NC
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Nut Hypersensitivities Clinical Trial
Walnut Oral Immunotherapy for Tree Nut Allergy
Status: Upcoming, Phase I, II
Updated: 4/12/2013
mi
from
CHapel Hill, NC
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Dermatology / Plastic Surgery, Oncology Clinical Trial
KeraStat Skin Therapy in Treating Radiation Dermatitis in Patients With Newly Diagnosed Stage 0-IIIA Breast Cancer
Status: Upcoming
Updated: 6/18/2014
mi
from
Winston-Salem, NC
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Healthy Volunteer Clinical Trial
A Quantitative Optical Sensor to Monitor Vascular Physiology; A Healthy Volunteer Study
Status: Upcoming
Updated: 4/5/2016
mi
from
Durham, NC
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Heart Defects, Congenital Clinical Trial
Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery
Status: Upcoming, Phase IV
Updated: 12/31/1969
mi
from
Durham, NC
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Mouth, Edentulous Clinical Trial
Conventionally vs. Digitally Fabricated Complete Dentures: Clinical Treatment Outcome Differences
Status: Upcoming
Updated: 4/1/2016
mi
from
Chapel Hill, NC
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Nicotine Dependence Clinical Trial
The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Durham, NC
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Multiple Myeloma Clinical Trial
Selinexor, Carfilzomib, and Dexamethasone Versus Placebo, Carfilzomib, and Dexamethasone in Multiple Myeloma
Status: Upcoming, Phase II
Updated: 3/23/2016
mi
from
Cary, NC
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Laboratory Assay Clinical Trial
Collection of Biological and Environmental Samples and Clinical Data From Anonymous Adult Men and Women for Quality Control and Methods Development and Evaluation (ASCA)
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Research Triangle Park, NC
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Anxiety Depression Clinical Trial
A Stepped-Care Telehealth Approach To Treat Distress In Rural Cancer Survivors
Status: Upcoming
Updated: 4/24/2018
mi
from
Winston-Salem, NC
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Pulmonary / Respiratory Diseases Clinical Trial
Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use
Status: Upcoming, Phase II
Updated: 9/28/2017
mi
from
Charlotte, NC
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Prostate Cancer Clinical Trial
Physical Activity in Men Newly Diagnosed With Prostate Cancer: A Feasibility Study
Status: Upcoming
Updated: 12/29/2017
mi
from
Raleigh, NC
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Pathogen Transmission Clinical Trial
Emission Patterns of Respiratory Pathogens
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Anemia Clinical Trial
Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Greenville, NC
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Nephrology / Urology Clinical Trial
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Durham, NC
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Immunology / Infectious Diseases Clinical Trial
Increasing Engagement and Improving HIV Outcomes Via HealthMPowerment
Status: Upcoming
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Migraine Clinical Trial
A Study of Lasmiditan (LY573144) Over Four Migraine Attacks
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Durham, NC
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Oncology Clinical Trial
An Investigational Immuno-therapy Study of Relatlimab Plus Nivolumab Compared to Various Standard-of-Care Therapies in Previously Treated Participants With Recurrent, Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
Status: Upcoming, Phase II
Updated: 12/31/1969
mi
from
Chapel Hill, NC
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Insomnia Disorder Clinical Trial
Provider Supported Self-Help Cognitive Behavioral Therapy for Insomnia (Tele-Self CBTI)
Status: Upcoming
Updated: 12/31/1969
mi
from
Durham, NC
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Acute Graft-versus-Host Disease Clinical Trial
Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Durham, NC
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Relapsed Refractory Multiple Myeloma Clinical Trial
Myeloma-Developing Regimens Using Genomics (MyDRUG)
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
Charlotte, NC
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Hypertension Clinical Trial
Angiotensin II in General Anesthesia
Status: Upcoming, Phase I
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Cardiology / Vascular Diseases Clinical Trial
Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention
Status: Upcoming, Phase II
Updated: 12/31/1969
mi
from
Durham, NC
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Dementia Clinical Trial
D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care
Status: Upcoming
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Prostatic Neoplasms Clinical Trial
A Study of Apalutamide in Participants With High‑Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Greensboro, NC
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Cystic Fibrosis Clinical Trial
Multicenter Study of Patient-reported Gastrointestinal Symptoms in People With Cystic Fibrosis
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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End Stage Renal Failure on Dialysis Clinical Trial
A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Winston-Salem, NC
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Skin Health Clinical Trial
Efficacy of a Nutritional Supplement on Skin Health in Generally Healthy Adults
Status: Upcoming
Updated: 12/31/1969
mi
from
High Point, NC
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Posttraumatic Stress Disorder Clinical Trial
Narrative Exposure Therapy (NET)
Status: Upcoming
Updated: 12/31/1969
mi
from
Durham, NC
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Asthma Atopic Clinical Trial
Identification of Allergic Asthmatics Reactive to Felis Catus (Cat Hair) Allergen Inhalation
Status: Upcoming, Phase
Updated: 12/31/1969
mi
from
Chapel Hill, NC
Click here to add this to my saved trials
Endocrinology Clinical Trial
A Coordinated Parent/Child Dyad Weight Loss Intervention: Dyad Plus
Status: Upcoming
Updated: 12/31/1969
mi
from
Winston-Salem, NC
Click here to add this to my saved trials
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